Skip to main content

3 Result(s)

within Patricia Deng Remove this filter

and

  1. Article

    Open Access

    Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

    ADAR RNA editing enzymes are high-affinity dsRNA-binding proteins that deaminate adenosines to inosines in pre-mRNA hairpins and also exert editing-independent effects. We generated a Drosophila AdarE374A mutant ...

    Patricia Deng, Anzer Khan, Dionna Jacobson, Nagraj Sambrani… in Nature Communications (2020)

    Download PDF (1718 KB) View Article

  2. Article

    Open Access

    Genetic map** uncovers cis-regulatory landscape of RNA editing

    Adenosine-to-inosine (A-to-I) RNA editing, catalysed by ADAR enzymes conserved in metazoans, plays an important role in neurological functions. Although the fine-tuning mechanism provided by A-to-I RNA editing...

    Gokul Ramaswami, Patricia Deng, Rui Zhang, Mary Anna Carbone… in Nature Communications (2015)

    Download PDF (1653 KB) View Article

  3. No Access

    Article

    Identifying RNA editing sites using RNA sequencing data alone

    Highly accurate and sensitive predictions of RNA editing sites can be obtained using RNA sequencing data from multiple individuals or species, without relying on matched genomic DNA sequence. Reanalyzing exist...

    Gokul Ramaswami, Rui Zhang, Robert Piskol, Liam P Keegan, Patricia Deng… in Nature Methods (2013)