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Open AccessHelicobacter Pylori infection in children with inflammatory bowel disease: a prospective multicenter study
The relationship between Helicobacter-pylori(Hp)infection and inflammatory-bowel-disease(IBD) in pediatric-patients remains controversial. We aimed to assess the Hp-infection occurrence in newly-diagnosed pediatr...
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Article
Open AccessBest practices for the management of febrile seizures in children
Febrile seizures (FS) are commonly perceived by healthcare professionals as a self-limited condition with a generally ‘benign’ nature. Nonetheless, they frequently lead to pediatric consultations, and their ma...
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Article
Oxidative stress and optical coherence tomography angiography evaluation of choriocapillaris and retinal vessel density in children with obstructive sleep apnea
To investigate the vascular networks of the retina and choroid using optical coherence tomography angiography (OCTA) to identify early biomarkers of obstructive sleep apnea (OSA) severity and to evaluate corre...
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Article
Open AccessPediatric torticollis: clinical report and predictors of urgency of 1409 cases
To date, the etiology and risk factors of torticollis are still poorly defined in the pediatric literature. Especially in the Emergency Department (ED) scenario, it is critical to reliably distinguish benign a...
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Article
Open AccessSomatization in children and adolescents with headache: the role of attachment to parents
Primary headache is a common somatic disorder in childhood that significantly affects quality of life. The condition is strongly associated with a variety of internalizing and externalizing disorders, and seve...
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Article
Open AccessFactors associated with hospitalization in a pediatric population of rural Tanzania: findings from a retrospective cohort study
Despite pediatric acute illnesses being leading causes of death and disability among children, acute and critical care services are not universally available in low-middle income countries, such as Tanzania, e...
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Article
Open AccessThe impact of COVID-19 on menstrual cycle’s alterations, in relation to depression and sleep disturbances: a prospective observational study in a population of medical students
The sars-Cov-2 pandemic has determined psychological stress, particularly in the young population of medical students. We studied the impact of the pandemic on menstrual cycle alteration in relation to psychol...
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Article
Open AccessChronic intestinal pseudo-obstruction: associations with gut microbiota and genes expression of intestinal serotonergic pathway
Pediatric chronic intestinal pseudo-obstruction (PIPO) is a rare disease characterized by symptoms and radiological signs suggestive of intestinal obstruction, in the absence of lumen-occluding lesions. It res...
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Article
Open AccessGastrointestinal bleeding in children: diagnostic approach
Different conditions may underlie gastrointestinal bleeding (GIB) in children. The estimated prevalence of GIB in children is 6.4%, with spontaneous resolution in approximately 80% of cases. Nonetheless, the i...
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Article
Open AccessQuantitative ultrasonographic examination of cerebral white matter by pixel brightness intensity as marker of middle-term neurodevelopment: a prospective observational study
Non-cystic white matter (WM) injury has become prevalent among preterm newborns and is associated with long-term neurodevelopmental impairment. Magnetic resonance is the gold-standard for diagnosis; however, c...
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Autonomic Involvement in Childhood Epilepsy
Autonomic symptoms are clinical manifestations of a wide range of epileptic seizures resulting from the recruitment or dysfunction of specific areas of the brain, best known as the central autonomic network. A...
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Article
Open AccessCyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)
Cyclic Vomiting Syndrome (CVS) is a rare functional gastrointestinal disorder, which has a considerable burden on quality of life of both children and their family. Aim of the study was to evaluate the diagnos...
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Article
Open AccessNeurological vertigo in the emergency room in pediatric and adult age: systematic literature review and proposal for a diagnostic algorithm
Neurological vertigo is a common symptom in children and adults presenting to the emergency department (ED) and its evaluation may be challenging, requiring often the intervention of different medical specialt...
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Article
Open AccessA dangerous food binge: a case report of hypokalemic periodic paralysis and review of current literature
Hypokalemic periodic paralysis is a rare neuromuscular genetic disorder due to defect of ion channels and subsequent function impairment. It belongs to a periodic paralyses group including hyperkalemic periodi...
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Open AccessReasons for SARS-CoV-2 infection in children and their role in the transmission of infection according to age: a case-control study
The locations where children get exposed to SARS-CoV-2 infection and their contribution in spreading the infection are still not fully understood. Aim of the article is to verify the most frequent reasons for ...
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Open AccessEffects of early energy intake on neonatal cerebral growth of preterm newborn: an observational study
Current guidelines for preterm newborns recommend high energy nutrition soon after birth in order to limit growth retardation. However, long-term effects of this nutritional approach are still debated, and it ...
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Photosensitivity in Various Disease States
Photosensitivity or “visual sensitivity” is in the literature used in different ways: (1) the focal or generalized epileptiform EEG reaction to Intermittent Photic Stimulation (IPS) or other visual stimuli, so...
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Article
Open AccessFaecal calprotectin and ultrasonography as non-invasive screening tools for detecting colorectal polyps in children with sporadic rectal bleeding: a prospective study
Colorectal polyps are reported in 6,1% of paediatric colonoscopies and in 12% of those performed for lower gastrointestinal bleeding. Although colonoscopy is widely used in paediatric patients, it requires bow...
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Article
Open AccessAn observational study of fixed-dose Tanacetum parthenium nutraceutical preparation for prophylaxis of pediatric headache
Migraine is one of the most prevalent chronic pain manifestations of childhood. Despite the multitude of available treatments, parents are often concerned about chronic therapies and pediatricians have insuffi...
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Open AccessA cohort study on acute ocular motility disorders in pediatric emergency department
Acute ocular motility disorders (OMDs) in children admitted to Emergency Department (ED) represents a not so rare condition with a wide spectrum of different etiologies. The emergency physician must be skilled...