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within Biomedicine Remove this filter Biomedical Engineering and Bioengineering Remove this filter Paolo Colombo Remove this filter

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  1. No Access

    Article

    Accessorized DPI: a Shortcut towards Flexibility and Patient Adaptability in Dry Powder Inhalation

    In this work, a novel powder dispersion add-on device, the AOS (Axial Oscillating Sphere), was studied in conjunction with commercially available DPI devices to improve the powder dispersion.

    Francesca Buttini, James Hannon, Kristi Saavedra, Irene Rossi… in Pharmaceutical Research (2016)

  2. No Access

    Article

    Biological Effects of Simvastatin Formulated as pMDI on Pulmonary Epithelial Cells

    The aim of this study is to evaluate the biological effects of Calu-3 epithelial cells in response to the delivery of simvastatin (SV) via solution pressurized metered dose inhaler (pMDI).

    Alaa S. Tulbah, Hui **n Ong, Wing-Hin Lee, Paolo Colombo… in Pharmaceutical Research (2016)

  3. No Access

    Article

    Pulmonary Spray Dried Powders of Tobramycin Containing Sodium Stearate to Improve Aerosolization Efficiency

    Tobramycin microparticulate powders containing the hydrophobic adjunct sodium stearate were studied for their use as pulmonary formulations in dry powder inhalers.

    Chiara Parlati, Paolo Colombo, Francesca Buttini, Paul M. Young… in Pharmaceutical Research (2009)

  4. No Access

    Article

    Physical and Chemical Enhancement of Transdermal Delivery of Triptorelin

    Sara Nicoli, Silvia Rimondi, Paolo Colombo, Patrizia Santi in Pharmaceutical Research (2001)

  5. No Access

    Article

    Ionized Prodrugs of Dehydroepiandrosterone for Transdermal lontophoretic Delivery

    Purpose. The aim of this work was to synthesize ionized dehydroepiandrosterone (DHEA) prodrugs with higher water solubility, useful for iontophoretic transdermal application.

    Sonia Laneri, Antonia Sacchi, Enrico Abignente di Frassello… in Pharmaceutical Research (1999)

  6. No Access

    Article

    Drug Reservoir Composition and Transport of Salmon Calcitonin in Transdermal Iontophoresis

    Purpose. The aim of the work was to study iontophoretic transdermal administration of salmon calcitonin (sCt) in rabbits, with particular attention to drug reservoir composition. A dry sCt disc, to be dissolved ...

    Patrizia Santi, Paolo Colombo, Ruggero Bettini… in Pharmaceutical Research (1997)

  7. No Access

    Article

    Delivery of Nasal Powders of β-Cyclodextrin by Insufflation

    Purpose. Delivery of nasal powders of granulated β-cyclodextrin by insufflation was studied in order to find the relationship between powder properties and delivery behavior.

    Alessia De Ascentiis, Ruggero Bettini, Giovanni Caponetti… in Pharmaceutical Research (1996)

  8. No Access

    Article

    Iontophoresis Enhances the Transport of Acyclovir Through Nude Mouse Skin by Electrorepulsion and Electroosmosis

    Purpose. Iontophoresis was employed for enhancing the transdermal delivery of acyclovir through nude mouse skin in vitro, with the aim of understanding the mechanisms responsible for drug transport, in order to ...

    Nadia Maria Volpato, Patrizia Santi, Paolo Colombo in Pharmaceutical Research (1995)

  9. No Access

    Article

    Letters to the Editor

    Paolo Colombo, ** I. Lee, Nikolaos A. Peppas… in Pharmaceutical Research (1990)

  10. No Access

    Article

    Drug/Polymer Matrix Swelling and Dissolution

    The swelling and dissolution behavior of pharmaceutical systems containing a drug and a polymer can be analyzed by a mathematical model which predicts the drug released and the gel layer thickness as a functio...

    Ronald S. Harland, Andrea Gazzaniga, M. Edvige Sangalli… in Pharmaceutical Research (1988)