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Article
Open AccessSocioeconomic disparities and the genomic landscape of gastric cancer
The genomic characteristics of Peruvian patients with gastric adenocarcinoma from diverse socioeconomic backgrounds were examined in consideration of the possibility that patients from different socioeconomic ...
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Article
Open AccessNovel domain-specific POU3F4 mutations are associated with X-linked deafness: examples from different populations
Mutations in the POU3F4 gene cause X-linked deafness type 3 (DFN3), which is characterized by inner ear anomalies.
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Article
Open AccessThe Int7G24A variant of transforming growth factor-beta receptor type I is a risk factor for colorectal cancer in the male Spanish population: a case-control study
The Int7G24A variant of transforming growth factor-beta receptor type I (TGFBR1) has been shown to increase the risk for kidney, ovarian, bladder, lung and breast cancers. Its role in colorectal cancer (CRC) has ...
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Article
Open AccessThe TGFBR1*6A allele is not associated with susceptibility to colorectal cancer in a Spanish population: a case-control study
TGF-β receptor type I is a mediator of growth inhibitory signals. TGFBR1*6A (rs11466445) is a common polymorphic variant of the TGF-β receptor I gene and has been associated with tumour susceptibility. Neverthele...
