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Article
Open AccessAstrocyte-derived hepcidin controls iron traffic at the blood-brain-barrier via regulating ferroportin 1 of microvascular endothelial cells
Brain iron dysregulation associated with aging is closely related to motor and cognitive impairments in neurodegenerative diseases. The regulation of iron traffic at the blood-brain barrier (BBB) is crucial to...
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Article
Stability and cytotoxicity of angiotensin-I-converting enzyme inhibitory peptides derived from bovine casein
This study investigated the effect of heat treatment combined with acid and alkali on the angiotensin-I- converting enzyme (ACE) inhibitory activity of peptides derived from bovine casein. The free amino group...
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Article
Upregulation of type I interleukin−1 receptor after traumatic spinal cord injury in adult rats
Post-traumatic inflammation response has been implicated in secondary injury mechanisms after spinal cord injury (SCI). Interleukin-1 (IL-1) is a key inflammatory mediator that is increasingly expressed after ...
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Article
Expression and localization of p80 interleukin-1 receptor protein in the rat spinal cord
The biological effects of interleukin (IL)-1 are mediated by two distinct receptors, the p80 or type I (IL-1RI) and p68 or type II (IL-1RII) receptors. Because IL-1RII has a short, 29-amino acid cytoplasmic do...