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Article
Heavy metal hydrolysis of polyisoprenoid-phosphate mono- and oligosaccarides
Mono- and oligosaccharide derivatives of dolichol phosphate can be hydrolyzed by heavy metal, preferably Zn++ at 100°C or 65°C. The reactions follow first order kinetics. The reaction proceeds through hydrolysis ...
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Article
Copper and zinc dismetabolism in the mouse brain upon chronic cuprizone treatment
Recent reports describe successful treatment using copper chelation therapy in neurodegenerative animal models. However, the success claimed for chelation therapy in neurodegenerative diseases is still rather ...
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Article
Aluminum-triggered structural modifications and aggregation of β-amyloids
We investigated the structural effects induced by Al3+ on different β-amyloid (Aβ) fragments at pH 7.4 and T= 25°C, with particular attention given to the sequences 1–40 and 1–42. Al3+ caused peptide enrichment i...