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    Article

    Effect of aluminum consumption on the vestibulo-ocular reflex

    The effects of chronic exposure (90 days) to Aluminum chloride (AlCl3) were analyzed in 3, 10 and 24 month old male rats (n=270) by investigating the function of the VOR (vestibulo-ocular reflex) in correlation w...

    O. Mameli, M. A. Caria, P. Melis, P. Zambenedetti, M. Ramila in Metabolic Brain Disease (2006)

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    Article

    Aluminum-triggered structural modifications and aggregation of β-amyloids

    We investigated the structural effects induced by Al3+ on different β-amyloid (Aβ) fragments at pH 7.4 and T= 25°C, with particular attention given to the sequences 1–40 and 1–42. Al3+ caused peptide enrichment i...

    F. Ricchelli, D. Drago, B. Filippi, G. Tognon in Cellular and Molecular Life Sciences CMLS (2005)

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    Article

    Copper and zinc dismetabolism in the mouse brain upon chronic cuprizone treatment

    Recent reports describe successful treatment using copper chelation therapy in neurodegenerative animal models. However, the success claimed for chelation therapy in neurodegenerative diseases is still rather ...

    P. Zatta, M. Raso, P. Zambenedetti in Cellular and Molecular Life Sciences CMLS (2005)

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    Chapter

    Aluminium(III) Speciation and Biological Effects

    Aluminium [Al(III)] is the third most abundant element as well as the most abundant metal-ion on the Earth’s crust. Apparently, Al(III) has no useful biological functions. However, few papers, as well as preli...

    P. Zatta, P. Zambenedetti in Cytotoxic, Mutagenic and Carcinogenic Pote… (1997)

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    Article

    Effects of tacrine upon murine neuroblastoma cells

    Tacrine [9-amino-1,2,3,4-tetrahydroacridine] (THA), a potent acetylcholinesterasic inhibitor, is utilized in the pharmacological treatment of Alzheimer's disease (Birne and Arie, 1994). Cytopharmacology of THA...

    P. Zatta, P. Zambenedetti, M. B. Marturano in Journal of Neural Transmission / General S… (1995)

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    Article

    Effects of aluminum speciation on murine neuroblastoma cells

    Murine neuroblastoma cells behave differently in the presence of Al(acac)3 [acac=2,4-pentanedionate; acetylacetonate] or Al(malt)3 [malt=3-hydroxy, 2-methyl, 4-pyronate; maltolate] with respect to Al(lac)3 [lac=2...

    P. Zatta, M. Perazzolo, L. Facci, S. D. Skaper in Molecular and Chemical Neuropathology (1992)

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    Article

    Dopamine, noradrenaline and serotonin during hypo-osmotic stress of Carcinus maenas

    Dopamine, noradrenaline and serotonin were measured in the haemolymph and gills of Carcinus maenas before and after transferring them into diluted seawater. A remarkable variation of the above-mentioned compounds...

    P. Zatta in Marine Biology (1987)

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    Chapter and Conference Paper

    Functional and Structural Properties of the 50,000 D Subunit of Octopus Vulgaris Hemocyanin

    Although the functional and structural properties of hemocyanins (Hc) have been well characterized (1,2), the interpretation of the results is often difficult owing to the quite complicated quaternary structur...

    F. Ricchelli, B. Filippi, S. Gobbo, E. Simoni in Invertebrate Oxygen Carriers (1986)

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    Chapter and Conference Paper

    Kinetics of Reaction Between Hemocyanin and CN- and of Reconstitution of Hemocyanin with K3Cu (CN)4

    It is well established that the addition of CN- to a native hemocyanin solution causes the release of oxygen and the blenching of the solution.

    B. Salvato, P. Zatta in Structure and Function of Haemocyanin (1977)

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    Article

    Heavy metal hydrolysis of polyisoprenoid-phosphate mono- and oligosaccarides

    Mono- and oligosaccharide derivatives of dolichol phosphate can be hydrolyzed by heavy metal, preferably Zn++ at 100°C or 65°C. The reactions follow first order kinetics. The reaction proceeds through hydrolysis ...

    P. Zatta in Experientia (1976)