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Article
Effect of aluminum consumption on the vestibulo-ocular reflex
The effects of chronic exposure (90 days) to Aluminum chloride (AlCl3) were analyzed in 3, 10 and 24 month old male rats (n=270) by investigating the function of the VOR (vestibulo-ocular reflex) in correlation w...
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Article
Aluminum-triggered structural modifications and aggregation of β-amyloids
We investigated the structural effects induced by Al3+ on different β-amyloid (Aβ) fragments at pH 7.4 and T= 25°C, with particular attention given to the sequences 1–40 and 1–42. Al3+ caused peptide enrichment i...
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Article
Copper and zinc dismetabolism in the mouse brain upon chronic cuprizone treatment
Recent reports describe successful treatment using copper chelation therapy in neurodegenerative animal models. However, the success claimed for chelation therapy in neurodegenerative diseases is still rather ...
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Chapter
Aluminium(III) Speciation and Biological Effects
Aluminium [Al(III)] is the third most abundant element as well as the most abundant metal-ion on the Earth’s crust. Apparently, Al(III) has no useful biological functions. However, few papers, as well as preli...
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Article
Effects of tacrine upon murine neuroblastoma cells
Tacrine [9-amino-1,2,3,4-tetrahydroacridine] (THA), a potent acetylcholinesterasic inhibitor, is utilized in the pharmacological treatment of Alzheimer's disease (Birne and Arie, 1994). Cytopharmacology of THA...
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Article
Effects of aluminum speciation on murine neuroblastoma cells
Murine neuroblastoma cells behave differently in the presence of Al(acac)3 [acac=2,4-pentanedionate; acetylacetonate] or Al(malt)3 [malt=3-hydroxy, 2-methyl, 4-pyronate; maltolate] with respect to Al(lac)3 [lac=2...
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Article
Dopamine, noradrenaline and serotonin during hypo-osmotic stress of Carcinus maenas
Dopamine, noradrenaline and serotonin were measured in the haemolymph and gills of Carcinus maenas before and after transferring them into diluted seawater. A remarkable variation of the above-mentioned compounds...
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Chapter and Conference Paper
Functional and Structural Properties of the 50,000 D Subunit of Octopus Vulgaris Hemocyanin
Although the functional and structural properties of hemocyanins (Hc) have been well characterized (1,2), the interpretation of the results is often difficult owing to the quite complicated quaternary structur...
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Chapter and Conference Paper
Kinetics of Reaction Between Hemocyanin and CN- and of Reconstitution of Hemocyanin with K3Cu (CN)4
It is well established that the addition of CN- to a native hemocyanin solution causes the release of oxygen and the blenching of the solution.
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Article
Heavy metal hydrolysis of polyisoprenoid-phosphate mono- and oligosaccarides
Mono- and oligosaccharide derivatives of dolichol phosphate can be hydrolyzed by heavy metal, preferably Zn++ at 100°C or 65°C. The reactions follow first order kinetics. The reaction proceeds through hydrolysis ...