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Article
Comparative differentiation analysis of distinct oral tissue-derived cells in response to osteogenic stimulation
Mixed cell populations from oral tissues may be superior to pure stem cells for regenerative approaches. Therefore, the aim of the present study was to explore the osteogenic potential of mixed cells derived f...
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Article
Expression of mRNAs encoding for growth factors, ECM molecules, and MMP13 in mono-cultures and co-cultures of human periodontal ligament fibroblasts and alveolar bone cells
Although the function and effects of many growth factors and extracellular matrix (ECM) molecules have been described for several periodontal tissues in vivo and in vitro, the molecular interactions involved i...
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Article
Morphogenesis and proliferation in mono- and organotypic co-cultures of primary human periodontal ligament fibroblasts and alveolar bone cells
Cells of the periodontal ligament and the alveolar bone lie in close vicinity in the periodontium. The goal of this study was to create an in vitro model to facilitate the study of the morphogenesis and prolif...
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Chapter
Tissue Models to Study Tumor-Stroma Interactions
The above summarized findings of this laboratory on tumor-stroma interactions, together with a growing number of other reports contribute to the accumulating evidence that the stromal part of epithelial tumors...
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Article
Connexin 43 expression is downregulated in raft cultures of human keratinocytes expressing the human papillomavirus type 16 E5 protein
A decrease in gap junction-mediated cell-to-cell communication has previously been observed in monolayer cultures of human keratinocytes (HaCaT cells) expressing the human papillomavirus type 16 E5 (HPV16 E5)...
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Article
Buchbesprechungen
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Article
Establishment of oral mucosa phenotype in vitro in correlation to epithelial anchorage
Cell-matrix interactions and the ordered deposition of basement membrane (BM) components are of major importance for the maintenance of tissue homeostasis in complex epithelia. This aspect was studied in vitro...
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Article
Integrins and tissue organization in epithelia of immortal (HACAT) and malignant cells in vitro
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Chapter and Conference Paper
Differentiation and Tumor Progression
Clinical and experimental experience indicate that differentiation and malignancy are inversely correlated. However, more recent experimental studies using mouse and human keratinocyte systems have demonstrate...
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Chapter and Conference Paper
Bullöses Pemphigoidantigen (BPA) und α6/β4-Integrin als Marker für frühe und späte Tumorprogession im In-vivo-Invasionsmodell und in HNO-Tumoren
Damit Tumorzellen invasiv werden bzw. metastasieren können, müssen am Interface zwischen Epithel bzw. Tumorinsel und umgebendem Bindegewebe Veränderungen in der Expression bestimmter Strukturproteine erfolgen....
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Chapter and Conference Paper
In Vitro Transformation and Tumor Progression
In recent years, our understanding of the genetic basis of cancer has been greatly enhanced by the discovery of molecular elements involved in cell transformation such as the oncogenes, capable of neoplastical...
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Article
Supplement II: Abstracts of the international symposium on Skin Carcinogenesis in man and in experimental models. Heidelberg, 29–31 October 1991 (pp S61–S88)
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