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  1. No Access

    Article

    Comparative differentiation analysis of distinct oral tissue-derived cells in response to osteogenic stimulation

    Mixed cell populations from oral tissues may be superior to pure stem cells for regenerative approaches. Therefore, the aim of the present study was to explore the osteogenic potential of mixed cells derived f...

    S. Proksch, K. Kirsch, K. Vach, E. Hellwig, P. Tomakidi in Clinical Oral Investigations (2019)

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    Article

    Expression of mRNAs encoding for growth factors, ECM molecules, and MMP13 in mono-cultures and co-cultures of human periodontal ligament fibroblasts and alveolar bone cells

    Although the function and effects of many growth factors and extracellular matrix (ECM) molecules have been described for several periodontal tissues in vivo and in vitro, the molecular interactions involved i...

    S. Winter, A. Kohl, A. Huppertz, C. Herold-Mende, T. Wiest in Cell and Tissue Research (2005)

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    Article

    Morphogenesis and proliferation in mono- and organotypic co-cultures of primary human periodontal ligament fibroblasts and alveolar bone cells

    Cells of the periodontal ligament and the alveolar bone lie in close vicinity in the periodontium. The goal of this study was to create an in vitro model to facilitate the study of the morphogenesis and prolif...

    T. Reuther, A. Kohl, G. Komposch, P. Tomakidi in Cell and Tissue Research (2003)

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    Chapter

    Tissue Models to Study Tumor-Stroma Interactions

    The above summarized findings of this laboratory on tumor-stroma interactions, together with a growing number of other reports contribute to the accumulating evidence that the stromal part of epithelial tumors...

    N. E. Fusenig, M. Skobe, S. Vosseler in Proteases and Their Inhibitors in Cancer M… (2002)

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    Article

    Connexin 43 expression is downregulated in raft cultures of human keratinocytes expressing the human papillomavirus type 16 E5 protein

    A decrease in gap junction-mediated cell-to-cell communication has previously been observed in monolayer cultures of human keratinocytes (HaCaT cells) expressing the human papillomavirus type 16 E5 (HPV16 E5)...

    P. Tomakidi, H. Cheng, A. Kohl, G. Komposch, A. Alonso in Cell and Tissue Research (2000)

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    Article

    Buchbesprechungen

    A. Demisch, P. Tomakidi in Journal of Orofacial Orthopedics / Fortsch… (2000)

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    Article

    Establishment of oral mucosa phenotype in vitro in correlation to epithelial anchorage

    Cell-matrix interactions and the ordered deposition of basement membrane (BM) components are of major importance for the maintenance of tissue homeostasis in complex epithelia. This aspect was studied in vitro...

    P. Tomakidi, D. Breitkreutz, N. E. Fusenig, J. Zöller, A. Kohl in Cell and Tissue Research (1998)

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    Article

    Integrins and tissue organization in epithelia of immortal (HACAT) and malignant cells in vitro

    D. Breitkreutz, M Bau, H -J Stark in Journal of Cancer Research and Clinical On… (1995)

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    Chapter and Conference Paper

    Differentiation and Tumor Progression

    Clinical and experimental experience indicate that differentiation and malignancy are inversely correlated. However, more recent experimental studies using mouse and human keratinocyte systems have demonstrate...

    N. E. Fusenig, D. Breitkreutz, P. Boukamp in Skin Cancer: Basic Science, Clinical Resea… (1995)

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    Chapter and Conference Paper

    Bullöses Pemphigoidantigen (BPA) und α64-Integrin als Marker für frühe und späte Tumorprogession im In-vivo-Invasionsmodell und in HNO-Tumoren

    Damit Tumorzellen invasiv werden bzw. metastasieren können, müssen am Interface zwischen Epithel bzw. Tumorinsel und umgebendem Bindegewebe Veränderungen in der Expression bestimmter Strukturproteine erfolgen....

    C. Herold-Mende, P. Tomakidi, A. I. Born, H. Discher, F. X. Bosch in Sitzungsbericht (1994)

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    Chapter and Conference Paper

    In Vitro Transformation and Tumor Progression

    In recent years, our understanding of the genetic basis of cancer has been greatly enhanced by the discovery of molecular elements involved in cell transformation such as the oncogenes, capable of neoplastical...

    P. Boukamp, D. Breitkreutz, A. Hülsen in Skin Carcinogenesis in Man and in Experime… (1993)

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    Article

    Supplement II: Abstracts of the international symposium on Skin Carcinogenesis in man and in experimental models. Heidelberg, 29–31 October 1991 (pp S61–S88)

    J. C. Barrett, C. A. Afshari, L. A. Annab in Journal of Cancer Research and Clinical On… (1991)

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    Article

    Absract

    Marietta Kaszkin, Volker Kinzel, Karl Maly in Journal of Cancer Research and Clinical On… (1991)