60 Result(s)

Article

Histidine decarboxylase (HDC) knock out mouse immune cells have altered expression of ACTH, triiodothyronine and endorphin

In earlier experiments the immune cells of HDC gene knock-out (HDC-KO) mice contained significantly more serotonin, than those of the wild ones. It was supposed that serotonin, being another biogenic amine, re...

G. Csaba, P. Kovács, E. Buzás, M. Mazán, É. Pállinger in Inflammation Research (2007)

Article

Serotonin content is elevated in the immune cells of histidine decarboxylase gene knock-out (HDCKO) mice. Focus on mast cells

Biogenic amines, histamine and serotonin are present in the granules and nucleus of mast cells. We wanted to study the presence, amount and localization of serotonin in mast cells and other cells of the immune...

G. Csaba, P. Kovács, E. Buzás, M. Mazán, É Pállinger in Inflammation Research (2007)

Article

How does the unicellular Tetrahymena utilise the hormones that it produces? Paying a visit to the realm of atto-and zeptomolar concentrations

Changes in the hormone content of Tetrahymena pyriformis GL were investigated during histamine, serotonin or insulin treatment at concentrations of 10⁻⁶M to 10⁻²¹M for 30 min. The immunologically demonstrable hor...

G. Csaba, P. Kovács, Éva Pállinger in Cell and Tissue Research (2007)

Article

Alcohol consumption during gestation reduces the histamine and triiodothyronine content of rat immune cells

Objective: Different factors acting during pregnancy can cause non-morphological alterations of cells which are manifested later, in adulthood. We studied the effect of maternal alcohol c...

G. Csaba, P. Kovács, É. Pállinger in Inflammation Research (2005)

Article

Invertase in Immobilized Cells of Eschscholtzia Californica

Cell suspension culture of Eschscholtzia californica Cham. were permeabilized by Tween 20 or 80, and immobilized by glutaraldehyde. The highest invertase activity was at pH 4.5 and temperature 50 °C. The hydrolys...

K. Neubert, J. Stano, K. Mičieta, P. Kovács, H. Tintemann in Biologia Plantarum (2002)

Article

Leukaemogenic potency of WEHI-3B cells grown in vitro or in leukaemic mice

In order to quantify contaminating leukaemia inducing cells in blood or bone marrow from WEHI-3B bearing BALB/c mice (injected with 10⁵ WEHI-3B suspension culture cells), in vitro colony forming leukaemia cells (...

J Gidáli, I Fehér, A Megyeri, P Kovács in Bone Marrow Transplantation (2001)

Article

Highly reduced peritoneal mast cell number and decreased c-kit expression in histidine decarboxylase knock out mice

Z. Wiener, E. Búzás, P. Kovács, G. Csaba, D. Szabó, Á. Kittel… in Inflammation Research (2001)

Article

Metabolic features in disease-resistant as well as in spontaneously hypertensive rats and newly established obese Wistar Ottawa Karlsburg inbred rats

OBJECTIVE: Studies, comparing several disease-prone and disease-resistant rat strains to elucidate the extent and severity of syndromes resembling human diseases are lacking. Therefore we studied the inbred ra...

J van den Brandt, P Kovács, I Klöting in International Journal of Obesity (2000)

Article

The Effect of β-Chloro D-Alanine and L-Cycloserine on The Serine, Phosphorus and Palmitic Acid Uptake and Metabolism of Tetrahymena Lipids

The serine palmitoyltransferase inhibitors β-chloro-D-alanine and L-cycloserine resulted in the uptake and metabolism of ³H-serine, ³H-palmitic acid and ³²P significant alterations in the unicellular Tetrahymena ...

P. Kovács in Acta Biologica Hungarica (1999)

Article

Imprinting Effects of Proline Containing Dipeptides (Proline-Glycine, Proline-Leucine, Proline-Valine and Their Retro Variants) in Tetrahymena. Evolutionary Conclusions

Proline-glycine, proline-leucine and proline-valine dipeptides and their retro variants were used in the experiments to study the effects of pretreatment (imprinting) in Tetrahymena, by investigating fluoresce...

G. Csaba, P. Kovács in Bioscience Reports (1997)

Article

A simple procedure for the detection of plant extracellular proteolytic enzymes

A simple procedure for the detection of extracellular plant proteolytic enzymes using insoluble dye stained gelatin substrates incorporated into an appropriate culture medium is described. Extracellular protei...

J. Stano, P. Kovács, I. Šafařík, D. Kákoniová, M. Šafaříková in Biologia Plantarum (1997)

Article

Treatment possibility of hypercholesterolaemia associated with hypertriglyceridaemia

Thirty patients were investigated with hyperlipoproteinaemia, 15 patients with non-insulin dependent diabetes mellitus (NIDDM) and 15 with primary hyperlipoproteinaemia. The patients took 250 mg acipimox (5-me...

G. Paragh, Z. Balogh, Judith Boda, P. Kovács, L. Kárpáti… in Acta Biologica Hungarica (1997)

Article

Chemotaxis of the unicellular green algaDunaliella salina and the ciliatedTetrahymena pyriformis—effects of glycine, lysine, and alanine, and their oligopeptides

Chemotactic properties of amino acids (L-alanine, glycine and L-lysine) and their oligopeptides (10⁻⁶M) and binding sites to these ligands were investigated in two unicellular models, the heterotrophicTetrahymena...

L. Köhidai, P. Kovács, G. Csaba in Bioscience Reports (1996)

Article

Catalase activity in develo** seedling of opium poppyPapaver somniferum L

Catalase is an enzyme unique to glyoxysomes in develo** poppy seedlings. Catalase activity is very low in endosperm and in embryo of germinating poppy seeds. During postgerminative growth and development the...

L. Bezáková, M. Mikuš, H. Šmorgovičova, P. Kovács, M. Pšenák in Biologia Plantarum (1996)

Article

Β-Galactosidase in immobilized cells ofPapaver somniferum

Cell suspension culture of poppy was permeabilized by Tween 80 and immobilized by glutaraldehyde. Β-Galactosidase showed optimum pH 4.8 and temperature of 50 ‡C. The enzyme hydrolysis was linear during 3 h rea...

J. Stano, P. Nemec, P. Kovács, D. Kákoniová, D. Liškov’a, K. Mičieta in Biologia Plantarum (1996)