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  1. Article

    Open Access

    Inner workings of thrombolites: spatial gradients of metabolic activity as revealed by metatranscriptome profiling

    Microbialites are sedimentary deposits formed by the metabolic interactions of microbes and their environment. These lithifying microbial communities represent one of the oldest ecosystems on Earth, yet the mo...

    J. M. Mobberley, C. L. M. Khodadad, P. T. Visscher, R. P. Reid… in Scientific Reports (2015)

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    Article

    Acidic vesicles of Schistosoma mansoni

    The fluorescent probe LysoTracker Red was used to examine for the presence of acidic vesicles in cercariae and schistosomula of Schistosoma mansoni. Acidic vesicles were widely distributed throughout the body of...

    P. Carneiro-Santos, J. Thornhill, M. Doenhoff, P. Hagan, J. Kusel in Parasitology Research (2001)

  3. No Access

    Article

    Seeking the ghost of worms past

    The mechanisms of protective immunity to parasite infections in humans are still elusive. Here, Woolhouse and Hagan discuss new evidence suggesting that the extremely slow development of acquired immunity to h...

    M.E.J. Woolhouse, P. Hagan in Nature Medicine (1999)

  4. No Access

    Article

    Partial characterization and kinetics of expression of Sm15, aSchistosoma mansoni tegumental antigen

    Differential antibody screening of an adultSchistosoma mansoni cDNA expression library constructed in lambda gt11 identified a partial cDNA clone, A70. This cDNA encodes a fusion protein recognized by antibodies ...

    F. G. C. Abath, P. Hagan, S. A. Jeffs, A. J. G. Simpson in Parasitology Research (1994)

  5. No Access

    Article

    Structure-activity relationships of various bisphosphonates

    A variety of bisphosphonates with aliphatic side chains of increasing length, as well as 3-amino-1-hydroxypropylidene-1,1-bisphosphonate (AHPrBP, formerly APD), dichloromethylenebisphosphonate (Cl2MBP, formerly C...

    H. Shinoda, G. Adamek, R. Felix, H. Fleisch, R. Schenk… in Calcified Tissue International (1983)

  6. No Access

    Chapter and Conference Paper

    Effect of Carrier on the Distribution of 54Mn and 67Ga in Tumor-Bearing Animals

    The simultaneous administration of carrier gallium has been shown [1] to change the biodistribution of carrier-free 67Ga from one of predominately soft-tissue distribution to localization primarily in bone and ki...

    S. E. Halpern, P. Hagan in Frontiers in Nuclear Medicine (1980)

  7. No Access

    Chapter and Conference Paper

    The Effect of Continuous Infusion on Tissue Distribution of 54Mn and 67Ga in Tumor-Bearing Animals

    Our previous data indicates that 54Mn is cleared from the plasma at a rate such that only 0.1% remains in the blood of a rat 4 h after its injection [4] and the tracer becomes bound in the tissues to the extent t...

    P. Hagan, S. E. Halpern in Frontiers in Nuclear Medicine (1980)