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Article
Intrinsic Capacity as a Determinant of Physical Resilience in Older Adults
The traditional disease-oriented model of healthcare is inadequate to address the needs of the older population. Greater attention should be given to strategies that promote healthy aging. Recently proposed co...
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Article
Frailty in China: From Research to Practice
Although geriatric research in general has increased in recent years, there is no effective treatment for frailty. Among older adults, those with frailty have an increased risk of falls, disability, and death....
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Article
Prevention of COVID-19 in Older Adults: A Brief Guidance from the International Association for Gerontology and Geriatrics (IAGG) Asia/Oceania Region
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Article
Report from the First Clinical Trials on Alzheimer’s Disease (CTAD) Asia-China 2018 : Bringing together Global Leaders
Population of older adults in Asia, and particularly in China is increasing rapidly. Older population are at increased risk of Alzheimer’s disease (AD) and other dementias. Soon, the Chinese population with AD...
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Article
Novel Frailty Screening Questionnaire (FSQ) Predicts 8-Year Mortality in Older Adults in China
Although frailty status greatly impacts health care in countries with rapidly aging populations, little is known about the frailty status in Chinese older adults.
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Article
Prevention of Disability in the Frail Chinese Older Population
As aging is becoming a global phenomenon, the burden of population aging is increasing rapidly, and is soon expected to be the highest in low-and middle-income countries. China represents the world’s largest p...
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Article
Simple Physical Activity Index Predicts Prognosis in Older Adults: Bei**g Longitudinal Study of Aging
Frailty, which involves low physical activity (PA), is as a well-established factor of increased risk of hospitalization, disability, and mortality. To date, there are no specific tools to assess PA among Chin...
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Article
The Promise of Telemedicine for Movement Disorders: an Interdisciplinary Approach
Advances in technology have expanded telemedicine opportunities covering medical practice, research, and education. This is of particular importance in movement disorders (MDs), where the combination of diseas...
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Article
The burden and epidemiology of community-acquired central nervous system infections: a multinational study
Risk assessment of central nervous system (CNS) infection patients is of key importance in predicting likely pathogens. However, data are lacking on the epidemiology globally. We performed a multicenter study ...
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Article
Open AccessMulticentennial record of Labrador Sea primary productivity and sea-ice variability archived in coralline algal barium
Accelerated warming and melting of Arctic sea-ice has been associated with significant increases in phytoplankton productivity in recent years. Here, utilizing a multiproxy approach, we reconstruct an annually...
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Article
TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma
Advances made in pancreatic cancer therapy have been far from sufficient and have allowed only a slight improvement in global survival of patients with pancreatic ductal adenocarcinoma (PDA). Recent progresses...
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Article
Proteomic changes in Corbicula fluminea exposed to wastewater from a psychiatric hospital
The increase use of pharmaceutical compounds in veterinary practice and human population results in the ubiquitous presence of these compounds in aquatic ecosystems. Because pharmaceuticals are highly bioactiv...
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Article
Open AccessBacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide α-MSH, at the origin of eating disorders
The molecular mechanisms at the origin of eating disorders (EDs), including anorexia nervosa (AN), bulimia and binge-eating disorder (BED), are currently unknown. Previous data indicated that immunoglobulins (...
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Chapter and Conference Paper
4D-Video Usefulness For Tracking Respiration Motion in 4DCT Scans and Targeting Small Mobile Tumors
4DCT-based treatment plan, 4DCBCT-guided patient setup, and real-time tracking of target motion are essential for accurate stereotactic body radiotherapy (SBRT) of small mobile tumors. However, there is lack o...
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Article
Open AccessA hospital outbreak of seasonal influenza involving three health care workers – implications on the optimal choice of respiratory protection
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Article
Using the phase-field crystal method in the multi-scale modeling of microstructure evolution
The phase-field-crystal method is a new modeling technique that incorporates the periodic nature of a crystal lattice by considering a free energy functional that is minimized by periodic density fields. This ...
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Article
Use of convalescent plasma therapy in SARS patients in Hong Kong
In order to evaluate the efficacy of convalescent plasma therapy in the treatment of patients with severe acute respiratory syndrome (SARS), 80 SARS patients were given convalescent plasma at Prince of Wales H...
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Article
Using artificial anomalies to detect unknown and known network intrusions
Intrusion detection systems (IDSs) must be capable of detecting new and unknown attacks, or anomalies. We study the problem of building detection models for both pure anomaly detection and combined misuse and ...
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Article
Structural analysis of the chimeric CYP21P/CYP21 gene in steroid 21-hydroxylase deficiency
Congenital adrenal hyperplasia (CAH) is a common autosomal recessive disorder mainly caused by defects in the steroid 21-hydroxylase (CYP21) gene. More than 90% of CAH cases are caused by mutations of the CYP21 ...
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Article
Internal fixation of valgus-impacted humeral head fractures using the screw-wiring technique
Between February 1996 and July 2000 eight patients (ages 35–74 years) with nine severely impacted humeral head fractures were operated on with the aim of preserving the humeral heads. Patients were treated sur...
