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Article
Open AccessNutritional status as independent prognostic factor of outcome and mortality until five years after hip fracture: a comprehensive prospective study
We determined the prognostic value of nutritional status for outcome after hip fracture. Nutritional status was a strong independent prognostic factor for clinical outcome and 5-year mortality. Physical functi...
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Article
Evaluation of the Feasibility, Safety and Efficacy of the Use of Intravenous Infusions of Adenosine Triphosphate (ATP) in People Affected by Moderate to Severe Alzheimer’s Disease: A Double-Blind Masked Clinical Trial for Dose Finding
There are currently no drug therapies modifying the natural history of patients suffering Alzheimer’s disease (AD). Most recent clinical trials in the field include only subjects in early stage of the disease,...
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Article
Open AccessThe association between diabetes status, HbA1c, diabetes duration, microvascular disease, and bone quality of the distal radius and tibia as measured with high-resolution peripheral quantitative computed tomography—The Maastricht Study
In this small cross-sectional study of predominantly well-treated participants with relatively short-term type 2 diabetes duration, HbA1c > 7% (53 mmol/mol) was associated with lower cortical density and thick...
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Article
Open AccessThe association between glucose metabolism status, diabetes severity and a history of fractures and recent falls in participants of 50 years and older—the Maastricht Study
In this cohort of relatively young and well-treated participants with type 2 diabetes, we found no association between diabetes status and a history of previous fractures and recent falls. Furthermore, no asso...
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Article
Vegetarianism, low meat consumption and the risk of lung, postmenopausal breast and prostate cancer in a population-based cohort study
The few prospective studies that examined lung, female breast and prostate cancer risk in vegetarians have yielded mixed results, whereas none have studied the effects of low meat diets. Moreover, little is kn...
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Article
Open AccessAssociation of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients
The P2X7 receptor is thought to be involved in bone physiology in a pro-osteogenic manner. Therefore, we examined associations between genetic variations in the P2X7 receptor gene and bone mineral density (BMD). ...
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Article
Open AccessCost-effectiveness of nutritional intervention in elderly subjects after hip fracture. A randomized controlled trial
Hip fracture patients can benefit from nutritional supplementation during their recovery. Up to now, cost-effectiveness evaluation of nutritional intervention in these patients has not been performed. Costs of...
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Article
Child-care use and the association with body mass index and overweight in children from 7 months to 2 years of age
Studies regarding the association of child-care use with body mass index (BMI), overweight or obesity development show contradictory results. This study examined the relationship between child-care use and BMI z-...
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Article
Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: a meta-analysis of 27 studies
Several case-control studies have examined the association between the Gly972Arg variant in the IRS-1 gene and Type 2 diabetes, but most had limited power and results could therefore be conflicting.
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Article
Pharmacokinetics of intravenous ATP in cancer patients
Objective: To characterise the pharmacokinetics of adenosine 5′-triphosphate (ATP) in patients with lung cancer after i.v. administration of different ATP dosages.
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Chapter and Conference Paper
Vegetarische und makrobiotische Ernährung bei Kindern: Forschungsergebnisse und Erfahrungen in den Niederlanden 1981–1993
Alternative Ernährungformen sind gewöhnlich durch eine gewisse Einschränkung des Konsums tierischer Produkte gekennzeichnet. Vor allem für Kinder besteht daher die Befürchtung, daß ein Mangel an gewissen Nährs...
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Article
Methylmalonic Acid and Homocysteine in Plasma as Indicators of Functional Cobalamin Deficiency in Infants on Macrobiotic Diets
ABSTRACT: Methylmalonic acid and total honnxyslcine in plasma and scrum have previously been used as indicators of intracellular cobalamin function in adults. To assess the usefulness of quantitation of these ...
