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Chapter and Conference Paper
Classifications, thésaurus, recommandations, référentiels, RCP et sites en ligne : entraînent-ils des dysfonctionnements de prise en charge?
La décision médicale, en particulier en cancérologie, est de plus en plus assistée par des référentiels s’appuyant sur des classifications, des thésaurus, des avis d’experts et des recommandations. Les informa...
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Chapter and Conference Paper
Lésions précancéreuses et cancers du sein : en fait-on assez ou en fait-on trop?
Le développement du dépistage des cancers du sein permet la découverte de lésions de faibles dimensions dont nous apprécions encore mal les risques et le potentiel évolutif. Contemporainement, l’évolution de n...
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Article
Open AccessEpstein-Barr virus as a marker of biological aggressiveness in breast cancer
Although a potential role of the Epstein-Barr virus (EBV) in the pathogenesis of breast cancer (BC) has been underlined, results remain conflicting. Particularly, the impact of EBV infection on biological mark...
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Article
Open AccessQuantitative immunohistochemical expression of c Kit in breast carcinomas is predictive of patients' outcome
c Kit (CD117) expression in tissues has been reported as a relevant target for specific therapy in some human malignancies, but has been poorly documented in breast carcinomas
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Article
Open AccessConcomitant intensive chemoradiotherapy induction in non-metastatic inflammatory breast cancer: long-term follow-up
The aim of this study was to evaluate with a long follow-up the efficacy of concomitant chemoradiotherapy in non-metastatic inflammatory breast cancer (IBC) and to evaluate the breast conservation rate. Betwee...
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Article
Open Accessc-Met overexpression in inflammatory breast carcinomas: automated quantification on tissue microarrays
Inflammatory breast carcinoma (IBC) is a rare but aggressive tumour associated with poor outcome owing to early metastases. Increased expression of c-Met protein correlates with reduced survival and high metas...
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Chapter and Conference Paper
Prise en charge par le chirurgien d’une élévation du risque de cancer du sein
Les mastectomies prophylactiques bilatérales représentent le moyen le plus efficace pour diminuer le risque de cancer du sein et le risque de décès par cancer du sein dans le cadre des familles à risque élevé.
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Article
Open AccessPrediction of metastasis risk (11 year follow-up) using VEGF-R1, VEGF-R2, Tie-2/Tek and CD105 expression in breast cancer (n=905)
Neoangiogenesis in tumours contributes to the development of blood-borne metastases, and can be evaluated by markers of activated endothelial cells in preference to panendothelial markers. Our purpose was to d...
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Article
Open AccessFrequency and genome load of Epstein-Barr virus in 509 breast cancers from different geographical areas
Since the few data exploring a possible association between Epstein–Barr virus (EBV) and breast cancer are conflicting, we investigated this association together with the influences of geographical areas. 509 ...
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Chapter and Conference Paper
Analyses of Natm-Tunnels with 2-D And 3-D Finite Element Method
To model the NATM shotcrete method of tunnelling we apply both 2D and 3D discretisations. The more or less traditional 2D approach is computationally simple, but it requires certain assumptions about the so-ca...
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Article
c-erbB-2 oncoprotein detected by automated quantitative immunocytochemistry in breast carcinomas correlates with patients' overall and disease-free survival
The prognostic significance of c-erbB-2 oncoprotein overexpression detected in tumours by immunocytochemical assays (ICAs) was investigated in 148 breast carcinomas. ICAs were performed under optimal technical...
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Article
Monoclonal 3c6f9 distribution in human breast carcinomas: image cytometry of immunocytochemical assays
MoAbF9 immunoreactivity was investigated in frozen sections of 123 breast carcinomas using an avidin or streptavidin biotin peroxidase kit. A standardized computer image analysis system was used to evaluate im...
