22 Result(s)

Article

Comparative genomic evidence for the involvement of schizophrenia risk genes in antipsychotic effects

Genome-wide association studies (GWAS) for schizophrenia have identified over 100 loci encoding >500 genes. It is unclear whether any of these genes, other than dopamine receptor D₂, are immediately relevant to a...

Y Kim, P Giusti-Rodriguez, J J Crowley, J Bryois, R J Nonneman… in Molecular Psychiatry (2018)

Article

On polynomial rings over nil rings in several variables and the central closure of prime nil rings

We prove that the ring of polynomials in several commuting indeterminates over a nil ring cannot be homomorphically mapped onto a ring with identity, i.e. it is Brown-McCoy radical. It answers a question posed...

M. Chebotar, W.-F. Ke, P.-H. Lee, E. R. Puczyłowski in Israel Journal of Mathematics (2018)

Article

Partitioning heritability analysis reveals a shared genetic basis of brain anatomy and schizophrenia

Schizophrenia is a devastating neurodevelopmental disorder with a complex genetic etiology. Widespread cortical gray matter loss has been observed in patients and prodromal samples. However, it remains unresol...

P H Lee, J T Baker, A J Holmes, N Jahanshad, T Ge, J-Y Jung, Y Cruz… in Molecular Psychiatry (2016)

Article

Solvent–water extraction method for the evaluation of polycyclic aromatic hydrocarbons bioavailability in coal–tar-contaminated soils

A solvent–water extraction method was proposed as an assessment tool to estimate the bioavailability of polycyclic aromatic hydrocarbons in coal–tar-contaminated soils. The approach taken was to measure the pe...

P. H. Lee, K. P. Chao, S. K. Ong in International Journal of Environmental Sci… (2014)

Article

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder

Schizophrenia (SCZ) and bipolar disorder (BD) are highly heritable psychiatric disorders with overlap** susceptibility loci and symptomatology. We conducted a genome-wide association study (GWAS) of these di...

S E Bergen, C T O'Dushlaine, S Ripke, P H Lee, D M Ruderfer… in Molecular Psychiatry (2012)

Article

A genome-wide association study of attempted suicide

The heritable component to attempted and completed suicide is partly related to psychiatric disorders and also partly independent of them. Although attempted suicide linkage regions have been identified on 2p1...

V L Willour, F Seifuddin, P B Mahon, D Jancic, M Pirooznia… in Molecular Psychiatry (2012)

Article

On Andrunakievich’s chain and Koethe’s problem

In 1969 Andrunakievich asked whether one gets a ring without nonzero nil left ideals from an arbitrary ring R by factoring out the ideal A(R) which is the sum of all nil left ideals of R. Recently, it was shown t...

M. A. Chebotar, P. -H. Lee, E. R. Puczyłowski in Israel Journal of Mathematics (2010)

Chapter and Conference Paper

A Note on Polynomial Rings over Nil Rings

Let R be a nil ring with _p R = 0 for some prime number p. We show that the polynomial ring R[x,y] in two commuting indeterminates x, y over R cannot be homomorphicall...

M. A. Chebotar, W. -F. Ke, P. -H. Lee, E. R. Puczyłowski in Modules and Comodules (2008)

Article

Elective laparoscopically assisted sigmoidectomy for the sigmoid volvulus

The laparoscopic approach for the treatment of sigmoid volvulus has been a rare surgical indication. This phase 2 study investigated the feasibility and surgical outcomes of elective laparoscopic surgery for s...

J.-T. Liang, H.-S. Lai, P.-H. Lee in Surgical Endoscopy And Other Interventional Techniques (2006)

Article

The plasma alpha-synuclein levels in patients with Parkinson’s disease and multiple system atrophy

α-Synuclein, a synaptic protein of unknown function, is a major component of Lewy bodies and may play a role in the pathophysiological process of Parkinson’s disease (PD). In this study, we measured the plasma...

P. H. Lee, G. Lee, H. J. Park, O. Y. Bang, I. S. Joo… in Journal of Neural Transmission (2006)

Article

Laparoscopic abdominoperineal resection for lower rectal cancers

The appropriateness of the laparoscopic approach for the resection of rectal cancer has been controversial, although it is well established in colon cancer. This is a phase II study of laparoscopic abdominoper...

J.-T. Liang, H.-S. Lai, P.-H. Lee in Surgical Endoscopy And Other Interventional Techniques (2006)

Article

Circulating beta amyloid protein is elevated in patients with acute ischemic stroke

Recent clinical and experimental studies suggest that ischemic strokes may play an important role in the pathogenesis of Alzheimer’s disease (AD). Beta amyloid (Aβ), a major component of senile plaque in AD, i...

P. H. Lee, O. Y. Bang, E. M. Hwang, J. S. Lee, U. S. Joo… in Journal of Neural Transmission (2005)

Article

Speciation of Chromium in an Electroplating Sludge During Thermal Stabilization

C.-C. Ku, H. P. Wang, P.-H. Lee, M. C. Hsiao… in Bulletin of Environmental Contamination an… (2003)