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  1. No Access

    Article

    Initiation and promotion at different ages and doses in 2200 mice. III. Linear extrapolation from high doses may underestimate low-dose tumour risks

    The dose-response relationships from the data described in Paper I were analysed. Among unpromoted animals, only doses sufficient to cause ulceration with subsequent promotion due to wound healing caused a rap...

    F Stenbäck, R Peto, P Shubik in British Journal of Cancer (1981)

  2. No Access

    Article

    Initiation and promotion at different ages and doses in 2200 mice. II. Decrease in promotion by TPA with ageing

    Using the data described in Paper I, we compare the effects of the same treatment timings and doses given at different ages. Initiation with DMBA at 68 weeks of age, followed 3 weeks later by TPA, has a signif...

    F Stenbäck, R Peto, P Shubik in British Journal of Cancer (1981)

  3. No Access

    Article

    Initiation and promotion at different ages and doses in 2200 mice. I. Methods, and the apparent persistence of initiated cells

    Delay between initiation and promotion on mouse skin was in 1949 reported by Berenblum and Shubik not to affect tumour yields, and this led to the important concept of the irreversibility of initiation and sti...

    F Stenbäck, R Peto, P Shubik in British Journal of Cancer (1981)

  4. No Access

    Article

    Thyroid tumours in rats and hepatomas in mice after griseofulvin treatment

    Griseofulvin, an antibiotic used to treat dermatophystosis, was tested for carcinogenicity in mice, rats and hamsters. Three groups of mice and rats were given the drug in powdered diet in alternating 5-week p...

    M Rustia, P Shubik in British Journal of Cancer (1978)

  5. No Access

    Article

    Carcinogenic activity of hexacholorobenzene in hamsters

    HEXACHLOROBENZENE (HCB), has been widely used as a fungicide, is a contaminant of various pesticides including DACTHAL and pentachloronitrobenzene, and is also a byproduct in the manufacture of many chlorinate...

    J. R. P. CABRAL, P. SHUBIK, T. MOLLNER, F. RAITANO in Nature (1977)

  6. Article

    Ascorbic acid and nitrosamines

    S. S. MIRVISH, P. SHUBIK in Nature (1974)

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  7. No Access

    Article

    Carcinogen — Induced skin tumorigenesis in mice: Enhancement and inhibition by ultraviolet light

    The effect of a single application of UV light as well as repeated applications of UV light on skin tumorigenesis in mice induced by 7,12-dimethylbenz(a)anthracene was studied. A single subcarcinogenic applica...

    F. Stenbäck, P. Shubik in Zeitschrift für Krebsforschung und Klinische Onkologie (1973)

  8. No Access

    Article

    Synergistic effect of ferric oxide on dimethylnitrosamine carcinogenesis in the Syrian golden hamster

    The carcinogenic effect of dimethylnitrosamine (DMN) injected subcutaneously in Syrian golden hamsters as well as the synergistic effect of intratracheal instillations of ferric oxide were studied. DMN alone i...

    F. Stenback, A. Ferrero, R. Montesano… in Zeitschrift für Krebsforschung und Klinisc… (1973)

  9. No Access

    Chapter and Conference Paper

    Evaluation of Possible Carcinogenicity of Petroleum Products in Therapeutic Use

    Many industrial products in common medicinal and cosmetic use vary widely in chemical composition. While some samples are highly refined, others might be much less so. This is certainly true of a residual mate...

    W. Li**sky, U. Saffiotti, P. Shubik in Potential Carcinogenic Hazards from Drugs (1967)

  10. No Access

    Article

    Carcinogenesis in Lewis Rats Injected at Birth with 7,12-Dimethylbenz(a)anthracene

    B Toth, P Shubik in British Journal of Cancer (1963)

  11. No Access

    Article

    The Occurrence of Malignant Lymphomas in Urethan-treated Swiss Mice

    B Toth, G Della Porta, P Shubik in British Journal of Cancer (1961)

  12. No Access

    Article

    The Role of Burning in Carcinogenesis

    U Saffiotti, P Shubik in British Journal of Cancer (1956)

  13. No Access

    Article

    The Persistence of Latent Tumour Cells Induced in the Mouse's Skin by a Single Application of 9:10-Dimethyl-1:2-Benzanthracene

    I Berenblum, P Shubik in British Journal of Cancer (1949)

  14. No Access

    Article

    An Experimental Study of the Initiating Stage of Carcinogenesis, and a Re-examination of the Somatic Cell Mutation Theory of Cancer

    I Berenblum, P Shubik in British Journal of Cancer (1949)

  15. No Access

    Article

    The Role of Croton Oil Applications, Associated with a Single Painting of a Carcinogen, in Tumour Induction of the Mouse's Skin

    I Berenblum, P Shubik in British Journal of Cancer (1947)

  16. No Access

    Article

    A New, Quantitative, Approach to the Study of the Stages of Chemical Carcinogenesis in the Mouse's Skin

    I Berenblum, P Shubik in British Journal of Cancer (1947)