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Article
Open AccessCirculating tumour cell detection: a direct comparison between the CellSearch System, the AdnaTest and CK-19/mammaglobin RT–PCR in patients with metastatic breast cancer
The detection, enumeration and isolation of circulating tumour cells (CTCs) have considerable potential to influence the clinical management of patients with breast cancer. There is, however, substantial varia...
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Article
Open AccessThe presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients
Circulating tumour cells (CTC) and tumour-related methylated DNA in blood have been separately assessed for their utility as a marker for subclinical metastasis in breast cancer. However, no studies have looke...
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Article
Open AccessPlasma fibrin D-dimer levels correlate with tumour volume, progression rate and survival in patients with metastatic breast cancer
Plasma levels of D-dimer are elevated in cancer patients. Activation of the extrinsic coagulation system and the fibrinolytic cascade within a tumour is thought to be related with growth, invasion and metastas...
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Article
Open AccessPlatelet number and interleukin-6 correlate with VEGF but not with bFGF serum levels of advanced cancer patients
We have compared the platelet number and the serum concentration of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and interleukin-6 (IL-6) in 80 blood samples of 50 patients ...
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Article
Open AccessProspective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer
Adjuvant treatment of patients with colorectal cancer is hampered by a lack of reliable prognostic factors in addition to the clinicopathological staging system. A poorly defined but considerable fraction of A...
