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  1. No Access

    Chapter and Conference Paper

    PSTN Enterprise Collaboration Systems

    Both intranet and extranet can be interchanged in Enterprise Collaboration System (ECS). However, it still has some limitations and challenges are faced by the organization due to connection issues. System con...

    P. S. JosephNg, R. C. Yeo, J. H. Wong in Pervasive Computing and Social Networking (2023)

  2. No Access

    Article

    Heterologous expression of a novel Poa pratensis gibberellin 2-oxidase gene, PpGA2ox, caused dwarfism, late flowering, and increased chlorophyll accumulation in Arabidopsis

    Gibberellin 2-oxidases (GA2oxs) irreversibly convert bioactive gibberellins (GAs) and their immediate precursors into inactive GAs via 2-β hydroxylation and so regulate gibberellin content in plants. However, to ...

    P.-H Tan, L. Zhang, S.-X. Yin, K. Teng in Biologia Plantarum (2018)

  3. Article

    Open Access

    Prognostic factors in metaplastic carcinoma of the breast: a multi-institutional study

    Metaplastic breast carcinoma (MBC) is a rare type of breast cancer that has basal-like characteristics and is perceived to have poorer prognosis when compared with conventional no specific type/ductal carcinom...

    E A Rakha, P H Tan, Z Varga, G M Tse, A M Shaaban, F Climent in British Journal of Cancer (2015)

  4. Article

    Open Access

    ALDH1 expression is enriched in breast cancers arising in young women but does not predict outcome

    Tumours arising in younger women appear to be biologically more aggressive and tend to have a poorer outcome. Being relatively resistant to conventional treatments, breast cancer stem cells (CSCs) have been po...

    E Y Tan, A A Thike, P H Tan in British Journal of Cancer (2013)

  5. No Access

    Article

    Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population

    Genome-wide association studies (GWAS) have identified various genetic susceptibility loci for breast cancer based mainly on European-ancestry populations. Differing linkage disequilibrium patterns exist betwe...

    M. Chan, S. M. Ji, C. S. Liaw, Y. S. Yap, H. Y. Law in Breast Cancer Research and Treatment (2012)

  6. No Access

    Article

    The shear mode of multilayer graphene

    Raman spectroscopy has already proved to be a powerful tool for studying the properties of single graphene layers. It is now shown that this technique can also provide information on the interaction between gr...

    P. H. Tan, W. P. Han, W. J. Zhao, Z. H. Wu, K. Chang, H. Wang in Nature Materials (2012)

  7. Article

    Mesenchymal stem cells differentially mediate regulatory T cells and conventional effector T cells to protect fully allogeneic islet grafts in mice

    Limited information is available on the cellular interactions between regulatory T (Treg) cells and mesenchymal stem cells (MSCs). In particular, a direct effect of MSCs on the survival and proliferation of Treg ...

    D. M. Xu, X. F. Yu, D. Zhang, M. X. Zhang, J. F. Zhou, P. H. Tan in Diabetologia (2012)

  8. No Access

    Chapter

    Nanotube and Graphene Polymer Composites for Photonics and Optoelectronics

    Polymer composites are an attractive near-term means to exploit the unique properties of single wall carbon nanotubes and graphene. This is particularly true for composites aimed at photonic and optoelectronic...

    T. Hasan, V. Scardaci, P.H. Tan, F. Bonaccorso, A.G. Rozhin in Molecular- and Nano-Tubes (2011)

  9. No Access

    Article

    A right renal angiomyolipoma with IVC thrombus and pulmonary embolism

    Angiomyolipomas (AML) are benign lesions, commonly found in the kidney, where they may be single or multiple. There is a high association with tuberous sclerosis or lymphangioleiomyomatosis. When found as a so...

    Y. S. Tan, K. H. Yip, P. H. Tan, W. S. Cheng in International Urology and Nephrology (2010)

  10. No Access

    Article

    LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer

    Deletion of 11q23–q24 is frequent in a diverse variety of malignancies, including breast and colorectal carcinoma, implicating the presence of a tumor suppressor gene at that chromosomal region. We examined a ...

    D C T Ong, Y M Ho, C Rudduck, K Chin, W -L Kuo, D K H Lie, C L M Chua, P H Tan in Oncogene (2009)

  11. No Access

    Article

    The role of 5′ untranslated region in translational suppression of OKL38 mRNA in hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide. OKL38 is a pregnancy-induced growth inhibitory gene and its expression is lost in various breast cancer cell lines and kidney tumor. To...

    C K Ong, C Leong, P H Tan, T Van, H Huynh in Oncogene (2007)

  12. No Access

    Article

    Systemic administration of naked DNA with targeting specificity to mammalian kidneys

    A major challenge for gene therapy is to be able to deliver efficiently the gene of interest to specific cell types. Here we describe a safe and simple effective naked DNA gene delivery method, via inferior ve...

    X Wu, H Gao, S Pasupathy, P H Tan, L L Ooi, K M Hui in Gene Therapy (2005)

  13. No Access

    Chapter

    High-K Candidates for Use as the Gate Dielectric in Silicon Mosfets

    D.G. Schlom, C.A. Billman, J.H. Haeni in Thin Films and Heterostructures for Oxide … (2005)

  14. No Access

    Article

    Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat

    N-methyl-D-aspartate (NMDA) receptor activation, at the level of the spinal cord, has been shown to play an important role in the facilitation of nociception in several animal models. However, the use of NMDA ant...

    P-H Tan, L-C Yang, H-C Shih, K-C Lan, J-T Cheng in Gene Therapy (2005)

  15. No Access

    Article

    Optical Study of Localized and Delocalized States in GaAsN/GaAs

    Taking advantages of short pulse excitation and time-resolved photoluminescence (PL), we have studied the exciton localization effect in a number of GaAsN alloys and GaAsN/GaAs quantum wells (QWs). In the PL s...

    Z. Y. Xu, X. D. Luo, X. D. Yang, P. H. Tan, C. L. Yang in MRS Online Proceedings Library (2003)

  16. No Access

    Article

    Gastrointestinal stromal tumor of the anus

    We report a rare case of gastrointestinal tumor of the anus with an unusual presentation as a perianal lipoma. A 65-year-old man presented with a 2-month history of a painless perianal lump clinically resembli...

    G. Y. M. Tan, C. K. Chong, K. W. Eu, P. H. Tan in Techniques in Coloproctology (2003)

  17. No Access

    Article

    Self-assembled Si/Ge quantum dot structures for novel device applications

    The band structure of self-assembled Si/Ge quantum dot structures deposited by molecular beam epitaxy in the Stranski Krastanov growth mode is characterized by optical and electrical spectroscopy. Interband an...

    K. Brunner, D. Bougeard, A. Janotta, M. Herbst, P. H. Tan in MRS Online Proceedings Library (2002)

  18. Article

    Open Access

    Metallothionein 1E mRNA is highly expressed in oestrogen receptor-negative human invasive ductal breast cancer

    Metallothioneins (MTs), a group of ubiquitous metalloproteins, comprise isoforms encoded by ten functional genes in humans. Different MT isoforms possibly play different functional roles during development or ...

    R **, B H Bay, V T K Chow, P H Tan, V C L Lin in British Journal of Cancer (2000)

  19. No Access

    Article

    Alternate Gate Oxides for Silicon Mosfets Using High- k Dielectrics

    High K (dielectric constant) and silicon-compatibility are essential for an alternative gate dielectric for use in silicon MOSFETs. Thermodynamic data were used to comprehensively evaluate the thermodynamic stabi...

    C. A. Billman, P. H. Tan, K. J. Hubbard, D. G. Schlom in MRS Online Proceedings Library (1999)