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  1. No Access

    Article

    Efficient nonviral Slee** Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity

    Genetically engineered lymphocytes hold promise for the treatment of genetic disease, viral infections and cancer. However, current methods for genetic transduction of peripheral blood lymphocytes rely on vira...

    P D Peng, C J Cohen, S Yang, C Hsu, S Jones, Y Zhao, Z Zheng, S A Rosenberg… in Gene Therapy (2009)

  2. No Access

    Article

    Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition

    In human gene therapy applications, lentiviral vectors may have advantages over γ-retroviral vectors in several areas, including the ability to transduce nondividing cells, resistance to gene silencing and a p...

    S Yang, C J Cohen, P D Peng, Y Zhao, L Cassard, Z Yu, Z Zheng, S Jones… in Gene Therapy (2008)