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Article
Open AccessChemogenetic inhibition of the lateral hypothalamus effectively reduces food intake in rats in a translational proof-of-concept study
Despite the therapeutic potential of chemogenetics, the method lacks comprehensive preclinical validation, hindering its progression to human clinical trials. We aimed to validate a robust but simple in vivo e...
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Article
Open AccessChromosome genomics facilitates the marker development and selection of wheat-Aegilops biuncialis addition, substitution and translocation lines
The annual goatgrass, Aegilops biuncialis is a rich source of genes with considerable agronomic value. This genetic potential can be exploited for wheat improvement through interspecific hybridization to increase...
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Article
Fine-scale analysis of the most important drivers of the Central European mosquito harm
Detailed knowledge of the habitat requirements of mosquitoes is essential for the targeted control of vectors. Our research sought to answer how the circumstances of fine-scale habitat affect the density of mo...
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Article
Open AccessStable carbon and nitrogen isotopes identify nuanced dietary changes from the Bronze and Iron Ages on the Great Hungarian Plain
The Great Hungarian Plain (GHP) served as a geographic funnel for population mobility throughout prehistory. Genomic and isotopic research demonstrates non-linear genetic turnover and technological shifts betw...
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Chapter
The International Criminal Court on the Rohingyas’ Situation and the Early Scholarly Echo of the Decision
It is often said that a judicial decision should speak for itself and judges participating in the decision making should refrain from explaining it ex post facto.
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Chapter
Interim Measures in the Practice of the International Court of Justice and the International Criminal Court
Comparative international jurisprudence is a precious tool in the hands of international lawyers to examine the increasing, and increasingly important, phenomenon of cross-fertilization among international cou...
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Article
Open AccessGenomic analysis of European bovine Staphylococcus aureus from clinical versus subclinical mastitis
Intramammary infections (IMI) with Staphylococcus aureus are a common cause of bovine mastitis and can result in both clinical (CM) or subclinical mastitis (SCM). Although bacterial isolates of S. aureus differ i...
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Chapter and Conference Paper
A Linear Parameter Varying ARX Model for Describing Biomedical Signal Couplings
Biomedical signal processing frequently deals with information extraction for clinical decision support. A major challenge in this field is to reveal diagnostic information by eliminating undesired interfering...
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Chapter and Conference Paper
Ensemble Learning for Heartbeat Classification Using Adaptive Orthogonal Transformations
In this work, we are focusing on the problem of heartbeat classification in electrocardiogram (ECG) signals. First we develop a patient-specific feature extraction scheme by using adaptive orthogonal transform...
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Article
Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab
Ipilimumab was the first immunotherapy approved for metastatic melanoma in decades and is currently registered as a second-line treatment. However, new immunotherapies, in combination with ipilimumab, offer ev...
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Article
Open AccessSoybean yield, biological N2 fixation and seed composition responses to additional inoculation in the United States
It is unclear if additional inoculation with Bradyrhizobia at varying soybean [Glycine max (L.) Merr.] growth stages can impact biological nitrogen fixation (BNF), increase yield and improve seed composition [pro...
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Chapter and Conference Paper
Adaptive Rational Transformations in Biomedical Signal Processing
In this paper we provide a summary on our recent research activity in the field of biomedical signal processing by means of adaptive transformation methods using rational systems. We have dealt with several qu...
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Article
Efficacy of Vemurafenib Treatment in 43 Metastatic Melanoma Patients with BRAF Mutation. Single-Institute Retrospective Analysis, Early Real-Life Survival Data
BRAF inhibitor vemurafenib achieved improved overall survival over chemotherapy and have been approved by the FDA and EMA for the treatment of BRAF-mutated metastatic melanoma. The aim of our retrospective ana...
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Article
A statistical method to estimate low-energy hadronic cross sections
In this article we propose a model based on the Statistical Bootstrap approach to estimate the cross sections of different hadronic reactions up to a few GeV in c.m.s. energy. The method is based on the idea, ...
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Chapter and Conference Paper
Rational Variable Projection Methods in ECG Signal Processing
In this paper we develop an adaptive electrocardiogram (ECG) model based on rational functions. We approximate the original signal by the partial sums of the corresponding Malmquist–Takenaka–Fourier series. Ou...
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Chapter
Admission into Diplomatic Buildings As an Alternative or Substitute to Diplomatic Asylum?
The 1961 Vienna Convention on Diplomatic Relations does not contain any explicit clause on diplomatic asylum. The temporary refuge offered by legations and embassies is however a currently used practice and st...
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Chapter
The International Criminal Court as an International Judicial Control of the National Public Power? (the ICC’s Standpoint on the Complementarity Principle in the Prosecutor V. Simone Gbagbo Case)
The article is about the interpretation of the complementarity principle of the Rome Statute. By this principle, the governments participating at the Rome Diplomatic Conference, wanted to match the general cla...
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Chapter and Conference Paper
ECG Signal Compression Using Adaptive Hermite Functions
In modern medical science evaluation of electrocardiogram (ECG) has proven to be an important task for doctors. These signals contain valuable information on the patients’ condition; however analysis of them h...
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Chapter
The Transfer of Sovereignty in the Case Law of the Hungarian Constitutional Court
The author analyzes the jurisprudence of the Hungarian Constitutional Court vis-à-vis the deepening of the supranational integration of the European Union.
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Article
Open AccessPseudopheochromocytoma induced by anxiolytic withdrawal
Symptomatic paroxysmal hypertension without significantly elevated catecholamine concentrations and with no evidence of an underlying adrenal tumor is known as pseudopheochromocytoma.