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Article
Open AccessCompliance with antibiotic therapy guidelines in french paediatric intensive care units: a multicentre observational study
Bacterial infections (BIs) are widespread in ICUs. The aims of this study were to assess compliance with antibiotic recommendations and factors associated with non-compliance.
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Chapter and Conference Paper
Identification of Ammonium Salts on Comet 67P/C-G Surface from Infrared VIRTIS/Rosetta Data Based on Laboratory Experiments. Implications and Perspectives
The nucleus of comet 67P/Churyumov-Gerasimenko exhibits a broad spectral reflectance feature around 3.2 µm, which is omnipresent in all spectra of the surface, and whose attribution has remained elusive since ...
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Article
Open AccessSimulation-based summative assessment in healthcare: an overview of key principles for practice
Healthcare curricula need summative assessments relevant to and representative of clinical situations to best select and train learners. Simulation provides multiple benefits with a growing literature base pro...
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Article
Open AccessFluid bolus therapy in pediatric sepsis: a narrative review
Leading cause of death in children under five, pediatric sepsis remains a significant global health threat. The 2020 Surviving Sepsis Campaign guidelines revised the management of septic shock and sepsis-assoc...
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Article
Lebensrettende Maßnahmen bei Kindern (Paediatric Life Support, PLS)
Die Leitlinien des European Resuscitation Council (ERC) zu den lebensrettenden Maßnahmen bei Kindern (Paediatric Life Support, PLS) basieren auf dem 2020 verfassten „International Consensus on Cardiopulmonary ...
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Article
Open AccessNecrotizing soft-tissue infections in pediatric intensive care: a prospective multicenter case-series study
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Article
Open AccessBrief summary of French guidelines for the prevention, diagnosis and treatment of hospital-acquired pneumonia in ICU
The French Society of Anaesthesia and Intensive Care Medicine and the French Society of Intensive Care edited guidelines focused on hospital-acquired pneumonia (HAP) in intensive care unit. The goal of 16 Fren...
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Article
A multicenter randomized controlled trial of a 3-L/kg/min versus 2-L/kg/min high-flow nasal cannula flow rate in young infants with severe viral bronchiolitis (TRAMONTANE 2)
High-flow nasal cannula (HFNC) therapy is increasingly proposed as first-line respiratory support for infants with acute viral bronchiolitis (AVB). Most teams use 2 L/kg/min, but no study compared different fl...
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Article
Open AccessTargeted temperature management in the ICU: guidelines from a French expert panel
Over the recent period, the use of induced hypothermia has gained an increasing interest for critically ill patients, in particular in brain-injured patients. The term “targeted temperature management” (TTM) h...
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Article
Open AccessExperts’ recommendations for the management of cardiogenic shock in children
Cardiogenic shock which corresponds to an acute state of circulatory failure due to impairment of myocardial contractility is a very rare disease in children, even more than in adults. To date, no internationa...
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Article
Open AccessInvasive fungal disease in PICU: epidemiology and risk factors
Candida and Aspergillus spp. are the most common agents responsible for invasive fungal infections in children. They are associated with a high mortality and morbidity rate as well as high health care costs. An ...
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Article
Patent Ductus Arteriosus in the Preterm Infant: A Survey of Clinical Practices in French Neonatal Intensive Care Units
Patent ductus arteriosus (PDA) is one of the most common problems in the care of premature infants, especially the extremely premature. There is no real consensus regarding the diagnostic criteria or treatment...
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Article
Severe transient ADAMTS13 deficiency in pneumococcal-associated hemolytic uremic syndrome
Thrombotic microangiopathies comprise different entities, including hemolytic uremic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP), and several other conditions. TTP is characterized by hemolytic a...
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Article
Paroxysmal extreme pain disorder: a molecular lesion of peripheral neurons
Choi et al. describe the case of a 3 month-old infant who, on the second day of life, had begun to experience painful paroxysmal events starting with tonic contraction of the whole body followed by erythematous h...
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Article
Short-Term Effect of Erythropoietin on Brain Lesions and Aquaporin-4 Expression in a Hypoxic-Ischemic Neonatal Rat Model Assessed by Magnetic Resonance Diffusion Weighted Imaging and Immunohistochemistry
Erythropoietin (Epo) is an endogenous cytokine that regulates hematopoiesis and is widely used to treat anemia. In addition, it has recently increased interest in the neurosciences since the new concept of Epo...
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Article
Chemical shift imaging and localised magnetic resonance spectroscopy in full-term asphyxiated neonates
Background: Diagnosis of brain lesions after birth anoxia-ischemia is essential for appropriate management. Clinical evaluation is not sufficient. MRI has been proven to provide useful information. Objective: To ...
