3 Result(s)
within
Olga Petrova
English
Neurosciences
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Article
Reversibility of Tau-Related Cognitive Defects in a Regulatable FTD Mouse Model
The accumulation of proteins such as Tau is a hallmark of several neurodegenerative diseases, e.g., frontotemporal dementia (FTD). So far, many mouse models of tauopathies have been generated by the use of mut...
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Article
Open AccessPreventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
Neurofibrillary tangles (NFT) composed of Tau are hallmarks of neurodegeneration in Alzheimer disease. Transgenic mice expressing full-length pro-aggregant human Tau (2N4R Tau-ΔK280, termed TauΔK) or its repeat d...
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Article
Open AccessAge-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD
Mutations of Tau are associated with several neurodegenerative disorders. Recently, the Tau mutation A152T was described as a novel risk factor for frontotemporal dementia spectrum disorders and Alzheimer dise...
