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  1. Article

    Open Access

    Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice

    Accumulation of amyloid-β plaques and tau contribute to the pathogenesis of Alzheimer’s disease (AD), but it is unclear whether targeting tau pathology by antioxidants independently of amyloid-β causes benefic...

    Ann Van der Jeugd, Arnaldo Parra-Damas, Raquel Baeta-Corral… in Scientific Reports (2018)

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  2. Article

    Open Access

    5th International Symposium on Focused Ultrasound

    Menashe Zaaroor, Alon Sinai, Dorit Goldsher… in Journal of Therapeutic Ultrasound (2016)

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  3. No Access

    Article

    Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau

    Neurofibrillary lesions of abnormal Tau are hallmarks of Alzheimer disease and frontotemporal dementias. Our regulatable (Tet-OFF) mouse models of tauopathy express variants of human full-length Tau in the for...

    Ann Van der Jeugd, Katja Hochgräfe, Tariq Ahmed, Jochen M. Decker… in Acta Neuropathologica (2012)

  4. No Access

    Article

    Reversibility of Tau-Related Cognitive Defects in a Regulatable FTD Mouse Model

    The accumulation of proteins such as Tau is a hallmark of several neurodegenerative diseases, e.g., frontotemporal dementia (FTD). So far, many mouse models of tauopathies have been generated by the use of mut...

    Astrid Sydow, Ann Van der Jeugd, Fang Zheng… in Journal of Molecular Neuroscience (2011)