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  1. Article

    Open Access

    Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional normalization method

    Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple methods have been suggested to date, but i...

    Henrik Bengtsson, Ola Hössjer in BMC Bioinformatics (2006)

  2. Article

    Open Access

    The genetic interacting landscape of 63 candidate genes in Major Depressive Disorder: an explorative study

    Genetic contributions to major depressive disorder (MDD) are thought to result from multiple genes interacting with each other. Different procedures have been proposed to detect such interactions. Which approa...

    Magnus Lekman, Ola Hössjer, Peter Andrews, Henrik Källberg, Daniel Uvehag in BioData Mining (2014)

  3. Article

    Open Access

    A significant risk locus on 19q13 for bipolar disorder identified using a combined genome-wide linkage and copy number variation analysis

    The genetic background to bipolar disorder (BPD) has been attributed to different genetic and genomic risk factors. In the present study we hypothesized that inherited copy number variations (CNVs) contribute ...

    Magnus Lekman, Robert Karlsson, Lisette Graae, Ola Hössjer, Ingrid Kockum in BioData Mining (2015)