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Article
Open AccessThe Diabetes teleMonitoring of patients in insulin Therapy (DiaMonT) trial: study protocol for a randomized controlled trial
The effect of telemedicine solutions in diabetes remains inconclusive. However, telemedicine studies have shown a positive trend in regards to glycemic control. The telemedicine interventions that facilitate a...
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Article
Open AccessReplication confers β cell immaturity
Pancreatic β cells are highly specialized to regulate systemic glucose levels by secreting insulin. In adults, increase in β-cell mass is limited due to brakes on cell replication. In contrast, proliferation i...
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Chapter
International Report
Trade secrets have been a legal concept since innovations made an impact on economy. Even during the Roman period, trade secrets were afforded legal protection. During the industrial revolution, courts introdu...
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Article
Pollutant Concentrations and Toxic Effects on the Red Alga Ceramium tenuicorne of Sediments from Natural Harbors and Small Boat Harbors on the West Coast of Sweden
This investigation set out to analyze the toxicity of surface sediments in a number of natural harbors and small boat harbors on the west coast of Sweden. This was done with the growth inhibition method with Cera...
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Chapter
Statistical Analysis of Single Nucleotide Polymorphism Microarrays in Cancer Studies
In this chapter, we focus on statistical questions raised by the identification of copy number alterations in tumor samples using genoty** microarrays, also known as Single Nucleotide Polymorphism (SNP) arra...
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Article
Open AccessTumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genoty** microarrays
High-throughput genoty** microarrays assess both total DNA copy number and allelic composition, which makes them a tool of choice for copy number studies in cancer, including total copy number and loss of he...
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Chapter and Conference Paper
A Measurement Framework for Team Level Assessment of Innovation Capability in Early Requirements Engineering
When develo** software-intensive products for a market-place it is important for a development organisation to create innovative features for coming releases in order to achieve advantage over competitors. T...
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Article
Open AccessMethodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional normalization method
Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple methods have been suggested to date, but i...
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Article
Open AccessMicroarray image analysis: background estimation using quantile and morphological filters
In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimate will have great influence on the final test...
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Article
Open AccessCalibration and assessment of channel-specific biases in microarray data with extended dynamical range
Non-linearities in observed log-ratios of gene expressions, also known as intensity dependent log-ratios, can often be accounted for by global biases in the two channels being compared. Any step in a microarra...
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Article
Particle Size Distributions of Clay-rich Sediments and Pure Clay Minerals: A Comparison of Grain Size Analysis with Sedimentation Field-Flow Fractionation
Two clay-rich coastal sediment samples have been characterised together with three pure clays identified as major components of the sediment samples. The mineralogy of the sediments was determined by X-ray dif...
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Article
Expression of serine/threonine kinase receptors including the bone morphogenetic factor type II receptor in the develo** and adult rat brain
The expression patterns of serine/threonine kinase receptors in the central nervous system of the develo** and adult rat were studied by in situ hybridization. The recently cloned bone morphogenetic factor r...
