4 Result(s)

Article

Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

In multiple myeloma malignant plasma cells expand within the bone marrow. Since this site is well-perfused, a rapid dissemination of “fitter” clones may be anticipated. However, an imbalanced distribution of m...

L. Rasche, S. S. Chavan, O. W. Stephens, P. H. Patel, R. Tytarenko… in Nature Communications (2017)

Article

Assessing the effect of obesity-related traits on multiple myeloma using a Mendelian randomisation approach

M Went, A Sud, P J Law, D C Johnson, N Weinhold, A Försti… in Blood Cancer Journal (2017)

Article

Genetic factors influencing the risk of multiple myeloma bone disease

A major complication of multiple myeloma (MM) is the development of osteolytic lesions, fractures and bone pain. To identify genetic variants influencing the development of MM bone disease (MBD), we analyzed M...

D C Johnson, N Weinhold, J Mitchell, B Chen, O W Stephens, A Försti, J Nickel… in Leukemia (2016)