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  1. No Access

    Article

    The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis

    The remodeling of calcium homeostasis contributes to the cancer hallmarks and the molecular mechanisms involved in calcium channel regulation in tumors remain to be characterized. Here, we report that SigmaR1,...

    M Gueguinou, D Crottès, A Chantôme, R Rapetti-Mauss, M Potier-Cartereau… in Oncogene (2017)

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    Article

    Function and regulation of TRPM7, as well as intracellular magnesium content, are altered in cells expressing ΔF508-CFTR and G551D-CFTR

    Cystic fibrosis (CF), one of the most common fatal hereditary disorders, is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene product is a multidomain adeno...

    F. Huguet, M. L. Calvez, N. Benz, S. Le Hir… in Cellular and Molecular Life Sciences (2016)

  3. Article

    Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells

    L-glutamate, the major excitatory neurotransmitter, also has a role in non-neuronal tissues and modulates immune responses. Whether NMDA receptor (NMDAR) signalling is involved in T-cell development is unknown...

    P Affaticati, O Mignen, F Jambou, M-C Potier… in Cell Death & Differentiation (2011)

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