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  1. Article

    Open Access

    Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR

    To determine the mechanisms associated with loss of androgen dependency and disease progression in prostate cancer (PCa), we investigated the relationship between the androgen receptor (AR) and mTOR pathways a...

    A Schayowitz, G Sabnis, O Goloubeva, V C O Njar, A M H Brodie in British Journal of Cancer (2010)

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    Article

    Phase II study of theophylline in chronic lymphocytic leukemia: a study of the Eastern Cooperative Oncology Group (E4998)

    The Eastern Cooperative Oncology Group (ECOG) performed a phase 2 study in B-cell chronic lymphocytic leukemia (CLL) of oral theophylline, a methylxanthine that inhibits cyclic nucleotide phosphodiesterases, t...

    P H Wiernik, E Paietta, O Goloubeva, S J Lee, D Makower, J M Bennett, J L Wade… in Leukemia (2004)