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Article
Open AccessProlonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR
To determine the mechanisms associated with loss of androgen dependency and disease progression in prostate cancer (PCa), we investigated the relationship between the androgen receptor (AR) and mTOR pathways a...
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Chapter
Test Generation: A Heuristic Approach
The adoption of the System-on-Chip design paradigm creates new challenges for designers and test engineers. In this chapter a high-level test generation approach is presented, which is able to produce high-qua...
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Article
Phase II study of theophylline in chronic lymphocytic leukemia: a study of the Eastern Cooperative Oncology Group (E4998)
The Eastern Cooperative Oncology Group (ECOG) performed a phase 2 study in B-cell chronic lymphocytic leukemia (CLL) of oral theophylline, a methylxanthine that inhibits cyclic nucleotide phosphodiesterases, t...
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Article
Hepatic veno-occlusive disease in children undergoing bone-marrow transplantation: usefulness of sonographic findings
Background. Reports of the usefulness of ultrasonography in the diagnosis of hepatic veno-occlusive disease (HVOD) have presented conflicting results.¶Objective. To determine the usefulness of gray-scale or Dopp...