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Article
Open AccessIncidence and associated factors of cetuximab-induced hypersensitivity infusion reactions in 1392 cancer patients treated in four French areas: a possible association with Lyme disease?
Previous studies have observed an increased incidence of Cetuximab-induced hypersensitivity infusion reactions (CI-IRs) in the southeastern states of the USA. Tick’s bites were suspected of generating cross-re...
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Article
Open AccessTime from first seen in specialist care to surgery does not influence survival outcome in patients with upfront resected pancreatic adenocarcinoma
This study evaluated the impact of time to surgery (TTS) on overall survival (OS), disease free survival (DFS) and postoperative complication rate in patients with upfront resected pancreatic adenocarcinoma (PA).
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Article
Extravasation médiastinale de chimiothérapie cytotoxique : à propos de deux cas
Les chambres implantables sont des dispositifs médicaux utilisés en oncologie pour l’administration par voie veineuse centrale de produits cytotoxiques, d’antibiotiques ou de nutrition parentérale. Les complic...
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Article
Open AccessSorafenib and irinotecan (NEXIRI) as second- or later-line treatment for patients with metastatic colorectal cancer and KRAS-mutated tumours: a multicentre Phase I/II trial
This trial evaluated the feasibility and efficacy of combined sorafenib and irinotecan (NEXIRI) as second- or later-line treatment of patients with KRAS-mutated metastatic colorectal cancer (mCRC), who had progre...
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Article
Les cancers de l’oesophage, de l’estomac et de la jonction oesogastrique (JOG) : une prise en charge résolument multidisciplinaire
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Article
Frequencies of KIT and PDGFRA mutations in the MolecGIST prospective population-based study differ from those of advanced GISTs
Gastrointestinal stromal tumors (GISTs) are the most common human sarcoma. Most of the data available on GISTs derive from retrospective studies of patients referred to oncology centers. The MolecGIST study so...
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Article
Management of cutaneous adverse events induced by anti-EGFR (epidermal growth factor receptor): a French interdisciplinary therapeutic algorithm
Cutaneous adverse events induced by epidermal growth factor receptor (EGFR) inhibitors can hamper the patients' quality of life. The aim of our work was to draft an algorithm for the optimised management of th...
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Article
Semiology of skin toxicity associated with epidermal growth factor receptor (EGFR) inhibitors
Advances in the understanding of the mechanisms involved in oncogenesis have led to the development of so-called targeted therapies such as epidermal growth factor receptor (EGFR) inhibitors, which take on an ...
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Article
Effets vasculaires et rénaux des médicaments anti-angiogéniques: recommandations françaises pour la pratique
Angiogenesis inhibitor drugs (bevacizumab, sunitinib, sorafenib, etc.) are now widely used for treatment of cancers, including colorectal, advanced renal-cell and hepatocellular carcinomas, breast cancer). Vas...
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Chapter
Pré-requis avant la mise en route d’une chimiothérapie pour cancer colorectal
Connaître les paramètres à prendre en considération avant la mise en route d’une chimiothérapie dans des conditions de sécurité optimales.
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Article
Open AccessMulticentre phase II trial of capecitabine plus oxaliplatin (XELOX) in patients with advanced hepatocellular carcinoma: FFCD 03-03 trial
Evaluation of new drug combinations is needed to improve patients' prognosis in advanced hepatocellular carcinoma (HCC). The purpose of this study was to evaluate the safety and efficacy of the capecitabine–ox...
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Article
Study of 47 consecutive patients with peptic esophageal stricture compared with 3880 cases of reflux esophagitis
The purpose of this study, making use of systematic records on computer over a period of 12 years, was to compare the prevalence and the demographic characteristics of patients with peptic stricture with those...
