30 Result(s)

Article

Flucloxacillin and cefazolin for treatment of Staphylococcus aureus bloodstream infection

Antistaphylococcal penicillins and cefazolin have been used as first line therapy in Methicillin-susceptible Staphylococcus aureus bloodstream infection. While efficacy of both regimens seems to be similar, th...

Kirsten Schmidt-Hellerau, Marianne Breuninger, Johanna Kessel… in Infection (2024)

Article

Outpatient parenteral antimicrobial therapy (OPAT) in Germany: insights and clinical outcomes from the K-APAT cohort study

Outpatient parenteral antimicrobial therapy (OPAT) offers several key advantages, including enhanced patient quality of life, reduced healthcare costs, and a potential reduction of nosocomial infections. It is...

Kirsten Schmidt-Hellerau, Nina Baade, Marina Günther, Nadine Scholten… in Infection (2024)

Article

Impact of a pediatric infectious disease consultation service on timely step-down to oral antibiotic treatment for bone and joint infections

In recent years an earlier step down to oral antibiotic therapy has been advocated for numerous infections. Trained infectious disease specialists regularly consulting their colleagues may speed up the impleme...

Katrin Mehler, André Oberthür, Ayla Yagdiran, Sarina Butzer, Norma Jung in Infection (2023)

Article

Specialized palliative care for hospitalized patients with SARS-CoV-2 infection: an analysis of the LEOSS registry

Symptom control for patients who were severely ill or dying from COVID-19 was paramount while resources were strained and infection control measures were in place. We aimed to describe the characteristics of S...

Kirsten Schmidt-Hellerau, Claudia Raichle, Maria M. Ruethrich… in Infection (2023)

Article

Brain abscess with Ureaplasma parvum in a patient with granulomatosis with polyangiitis

Ureaplasma species are associated with urogenital infections, infertility and adverse pregnancy outcomes as well as neonatal infections. Involvement of the central nervous system in adults is extremely rare. We r...

Marie Madlener, Marianne Breuninger, Arne Meißner, Henning Stetefeld… in Infection (2023)

Article

Choosing Wisely internationally – helpful recommendations for antimicrobial stewardship!

Antimicrobial resistance poses a major threat to human health globally and antibiotic overuse is a main driver of resistance. Antimicrobial stewardship (AMS) was developed to improve the rationale use of antib...

Norma Jung, Lukas Tometten, Rika Draenert in Infection (2023)

Article

Clinical features and outcome of vertebral osteomyelitis after spinal injection: is it worth the price?

Spinal injections are increasingly used for back pain treatment. Vertebral osteomyelitis (VO) after spinal injection (SIVO) is rare, but patient characteristics and outcome have not been well characterized. Th...

Ayla Yagdiran, Gregor Paul, Charlotte Meyer-Schwickerath… in Infection (2023)

Article

Prediction of COVID-19 deterioration in high-risk patients at diagnosis: an early warning score for advanced COVID-19 developed by machine learning

While more advanced COVID-19 necessitates medical interventions and hospitalization, patients with mild COVID-19 do not require this. Identifying patients at risk of progressing to advanced COVID-19 might guid...

Carolin E. M. Jakob, Ujjwal Mukund Mahajan, Marcus Oswald, Melanie Stecher… in Infection (2022)

Article

Establishment of an interdisciplinary board for bone and joint infections

The incidence of bone and joint infections is increasing while their treatment remains a challenge. Although guidelines and recommendations exist, evidence is often lacking and treatment complicated by complex...

Christina Otto-Lambertz, Ayla Yagdiran, Kirsten Schmidt-Hellerau… in Infection (2021)

Article

“Saying goodbye all alone with no close support was difficult”- Dying during the COVID-19 pandemic: an online survey among bereaved relatives about end-of-life care for patients with or without SARS-CoV2 infection

During the SARS-CoV2 pandemic, protection measures, as well as visiting restrictions, had a severe impact on seriously ill and dying patients and their relatives. The study aims to describe the experiences of ...

Karlotta Schloesser, Steffen T Simon, Berenike Pauli… in BMC Health Services Research (2021)

Article

Quality of life and mortality after surgical treatment for vertebral osteomyelitis (VO): a prospective study

Vertebral osteomyelitis (VO) has a high mortality and leads to chronic pain and functional disability. Surgical treatment is often necessary. To date, little is known about the consequences of surgery on patie...

Ayla Yagdiran, Christina Otto-Lambertz… in European Spine Journal (2021)

Article

Plasma interferon-γ-inducible protein 10 (IP-10) levels correlate with disease severity and paradoxical reactions in extrapulmonary tuberculosis

With 1.5 million deaths worldwide in 2018, tuberculosis (TB) remains a major global public health problem. While pulmonary TB (PTB) is the most common manifestation, the proportion of extrapulmonary TB (EPTB) ...

Isabelle Suárez, Samuel Rohr, Melanie Stecher, Clara Lehmann, Sandra Winter… in Infection (2021)

Article

Detection of SARS-CoV-2 viremia before onset of COVID-19 symptoms in an allo-transplanted patient with acute leukemia

Veronica Di Cristanziano, Charlotte Meyer-Schwickerath… in Bone Marrow Transplantation (2021)

Article

First results of the “Lean European Open Survey on SARS-CoV-2-Infected Patients (LEOSS)”

Knowledge regarding patients’ clinical condition at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection is sparse. Data in the international, multicenter Lean European Open Survey on SARS-Co...

Carolin E. M. Jakob, Stefan Borgmann, Fazilet Duygu, Uta Behrends… in Infection (2021)

Article

Update on the “Choosing Wisely” initiative in infectious diseases in Germany

The Choosing Wisely^® initiative is an international campaign addressing over- and underuse of diagnostic and therapeutic measures in infectious diseases among others. Since 2016, the German Society for Infectious...

Rika Draenert, Norma Jung in Infection (2020)

Article

The diagnostic value of soluble urokinase-type plasminogen activator receptor (suPAR) for the discrimination of vertebral osteomyelitis and degenerative diseases of the spine

There is still a challenge in discriminating between vertebral osteomyelitis and degenerative diseases of the spine. To this end, we determined the suitability of soluble urokinase-type plasminogen activator r...

Jan Simon Scharrenberg, Ayla Yagdiran… in Journal of Orthopaedic Surgery and Research (2019)