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Open AccessProtocol of a phase II study to evaluate the efficacy and safety of deep-inspiration breath-hold daily online adaptive radiotherapy for centrally located lung tumours (PUDDING study)
Centrally located lung tumours present a challenge because of their tendency to exhibit symptoms such as airway obstruction, atelectasis, and bleeding. Surgical resection of these tumours often requires sacrif...
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Article
New patient setup procedure using surface-guided imaging to reduce body touch and skin marks in whole-breast irradiation during the COVID-19 pandemic
This study aimed to assess the effectiveness of a new patient-setup procedure using surface-guided imaging during the coronavirus disease 2019 (COVID-19) pandemic for left-sided whole-breast irradiation with d...
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Article
Open AccessCorrection to: Therapeutic strategy for acute appendicitis based on laparoscopic surgery
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Article
Open AccessTherapeutic strategy for acute appendicitis based on laparoscopic surgery
The treatment strategies for acute appendicitis differ depending on the facility, and various studies have investigated the usefulness of conservative treatment with antibiotics, laparoscopic surgery, and inte...
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Article
Open AccessPhase I clinical trial of multiple-peptide vaccination for patients with advanced biliary tract cancer
The prognosis of patients with advanced biliary tract cancer (BTC) is extremely poor and only a few standard treatments are available for this condition. We performed a phase I trial to investigate the safety,...
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Article
Targeting MARCO can lead to enhanced dendritic cell motility and anti-melanoma activity
We reported that murine tumor lysate-pulsed dendritic cells (TP-DC) could elicit tumor-specific CD4+ and CD8+ T cells in vitro and in vivo. In some limited cases, TP-DC treatments in vivo could also result in reg...
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Article
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
Autophagy is an evolutionarily conserved 'self-eating' process. Although the genes essential for autophagy (named Atg) have been identified in yeast, the molecular mechanism of how Atg proteins control autophagos...