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Article
Astaxanthin Attenuates Nonalcoholic Steatohepatitis with Downregulation of Osteoprotegerin in Ovariectomized Mice Fed Choline-Deficient High-Fat Diet
Postmenopausal estrogen decline increases the risk of develo** nonalcoholic steatohepatitis (NASH), and it might accelerate progression to cirrhosis and hepatocellular carcinoma.
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Article
Open AccessA nanoscale metal organic frameworks-based vaccine synergises with PD-1 blockade to potentiate anti-tumour immunity
Checkpoint blockade therapy has provided noteworthy benefits in multiple cancers in recent years; however, its clinical benefits remain confined to 10–40% of patients with extremely high costs. Here, we design...
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Article
Open AccessThe molecular mechanism for activating IgA production by Pediococcus acidilactici K15 and the clinical impact in a randomized trial
IgA secretion at mucosal sites is important for host defence against pathogens as well as maintaining the symbiosis with microorganisms present in the small intestine that affect IgA production. In the present...
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Article
Open AccessAn optimistic protein assembly from sequence reads salvaged an uncharacterized segment of mouse picobirnavirus
Advances in Next Generation Sequencing technologies have enabled the generation of millions of sequences from microorganisms. However, distinguishing the sequence of a novel species from sequencing errors rema...
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Chapter and Conference Paper
Establishment of Dendritic Cell Line from Caspase-1-Deficient Mice
Dendritic cells (DC) are the most efficient antigen presenting cells and key players in the initiation and modulation of immune response. DC regulate the type of T cell response and play the crucial role in th...
