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  1. Article

    Metastatic myxofibrosarcoma of the spermatic cord responding to mesna, adriamycin, ifosfamide, and dacarbazine combination therapy

    Myxofibrosarcoma is common in the extremities of elderly people and is characterized by a high frequency of local recurrence. We report herein a case of a 72-year-old male who presented with a 5-year history o...

    Hideaki Ito, Nobuyuki Oyama, Yoshiji Miwa in International Cancer Conference Journal (2012)

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    Article

    Assessment of Therapeutic Effect of Sunitinib by 11C-Acetate PET Compared with FDG PET Imaging in a Patient with Metastatic Renal Cell Carcinoma

    Although sunitinib shows a high response rate in patients with untreated metastatic renal cell carcinoma (mRCC), quite a few patients show no therapeutic effect. Therefore, it is crucial to distinguish the pat...

    Nobuyuki Oyama, Noriko Takahara, Yoko Hasegawa in Nuclear Medicine and Molecular Imaging (2011)

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    Article

    Early response assessment in prostate carcinoma by 18F-fluorothymidine following anticancer therapy with docetaxel using preclinical tumour models

    The aim of the study was to assess the potential usefulness of 3-deoxy-3-18F-fluorothymidine (FLT) as a radiopharmaceutical for imaging the early therapeutic effects of docetaxel (DTX) on tumour proliferation in ...

    Nobuyuki Oyama, Yoko Hasegawa in European Journal of Nuclear Medicine and M… (2011)

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    Article

    Selective α1A-blocker improves bladder storage function in rats via suppression of C-fiber afferent activity

    In the present study, we used animal models to investigate whether the selective α1A-blocker silodosin exerts inhibitory effects on detrusor overactivity by modulating C-fiber afferent activity.

    Osamu Yokoyama, Hideaki Ito, Yoshitaka Aoki, Nobuyuki Oyama in World Journal of Urology (2010)

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    Article

    11C-Acetate PET imaging for renal cell carcinoma

    In this study, we investigated the effectiveness of positron emission tomography (PET) with 11C-acetate (AC) for evaluation of renal cell carcinoma.

    Nobuyuki Oyama, Hidehiko Okazawa in European Journal of Nuclear Medicine and M… (2009)

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    Article

    Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent Cu-diacetyl-bis(N 4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells

    The retention mechanism of the novel imaging/radiotherapeutic agent, Cu-diacetyl-bis(N 4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells was clarified in comparison with that in normal t...

    Atsushi Obata, Eiji Yoshimi, Atsuo Waki, Jason S. Lewis in Annals of Nuclear Medicine (2001)