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  1. No Access

    Article

    Circulating level of β-aminoisobutyric acid (BAIBA), a novel myokine-like molecule, is inversely associated with fat mass in patients with heart failure

    Results of experimental studies have shown that β-aminoisobutyric acid (BAIBA), an exercise-induced myokine-like molecule, is an endogenous negative regulator of fat mass in mice, but it remains unclear whethe...

    Satoshi Katano, Toshiyuki Yano, Hidemichi Kouzu, Ryohei Nagaoka in Heart and Vessels (2024)

  2. No Access

    Article

    Independent Association Between Use of Proton Pump Inhibitors and Muscle Wasting in Patients with Heart Failure: A Single-Center, Ambispective, Observational Study

    Although proton pump inhibitors (PPIs) play a pivotal role in the prevention and treatment of gastric acid-related diseases and gastrointestinal adverse events caused by antiplatelet therapies, the safety of l...

    Katsuhiko Ohori, Toshiyuki Yano, Satoshi Katano, Ryohei Nagaoka in Drugs & Aging (2023)

  3. Article

    Open Access

    Elevated circulating level of β-aminoisobutyric acid (BAIBA) in heart failure patients with type 2 diabetes receiving sodium-glucose cotransporter 2 inhibitors

    The mechanism by which a sodium-glucose cotransporter inhibitor (SGLT2i) induces favorable effects on diabetes and cardiovascular diseases including heart failure (HF) remains poorly understood. Metabolomics i...

    Satoshi Katano, Toshiyuki Yano, Hidemichi Kouzu in Cardiovascular Diabetology (2022)

  4. Article

    Open Access

    Descending thoracic aorta–abdominal aortic bypass and bilateral renal arterial blood circulation reconstruction are effective in atypical coarctation of the aorta with heart failure: a case report

    There are a lot of reports of the renal failure and heart failure due to coarctation of the aorta. However, there are no case reports in which revascularization dramatically improved left ventricular function ...

    Takuma Mikami, Takeshi Kamada, Toshiyuki Yano in Journal of Cardiothoracic Surgery (2021)

  5. Article

    Open Access

    Reduction in GLP-1 secretory capacity may be a novel independent risk factor of coronary artery stenosis

    Multiple factors regulate glucagon-like peptide-1 (GLP-1) secretion, but a group of apparently healthy subjects showed blunted responses of GLP-1 secretion in our previous study. In this study, we examined whe...

    Chihiro Nagase, Masaya Tanno, Hidemichi Kouzu, Takayuki Miki in Scientific Reports (2021)

  6. Article

    Open Access

    Energy intake during hospital stay predicts all-cause mortality after discharge independently of nutritional status in elderly heart failure patients

    Malnutrition is associated with an increased risk of mortality in heart failure (HF) patients. Here, we examined the hypothesis that assessment of energy intake in addition to nutritional status improves the s...

    Satoshi Katano, Toshiyuki Yano, Hidemichi Kouzu in Clinical Research in Cardiology (2021)

  7. Article

    Open Access

    High percent body fat mass predicts lower risk of cardiac events in patients with heart failure: an explanation of the obesity paradox

    Although high body mass index (BMI) is a risk factor of heart failure (HF), HF patients with a higher BMI had a lower mortality rate than that in HF patients with normal or lower BMI, a phenomenon that has bee...

    Katsuhiko Ohori, Toshiyuki Yano, Satoshi Katano, Hidemichi Kouzu in BMC Geriatrics (2021)

  8. Article

    Open Access

    Gas** during refractory out-of-hospital cardiac arrest is a prognostic marker for favourable neurological outcome following extracorporeal cardiopulmonary resuscitation: a retrospective study

    Gas** during cardiac arrest is associated with favourable neurological outcomes for out-of-hospital cardiac arrest. Moreover, while extracorporeal cardiopulmonary resuscitation (ECPR) performed for refractor...

    Naofumi Bunya, Hirofumi Ohnishi, Kenshiro Wada in Annals of Intensive Care (2020)

  9. No Access

    Article

    Assessment of prognosis in immunoglobulin light chain amyloidosis patients with severe heart failure: a predictive value of right ventricular function

    Although the benefit of updated therapeutic regimens, including bortezomib, on the survival of immunoglobulin light chain (AL) amyloidosis patients with heart failure (HF) has been reported, predictors of mort...

    Nobutaka Nagano, Toshiyuki Yano, Yugo Fujita, Hidemichi Kouzu in Heart and Vessels (2020)

  10. No Access

    Article

    Risk classification of pulmonary arterial hypertension by echocardiographic combined assessment of pulmonary vascular resistance and right ventricular function

    Which combination of clinical parameters improves the prediction of prognosis in patients with pulmonary arterial hypertension (PAH) remains unclear. We examined whether combined assessment of pulmonary vascul...

    Mina Kawamukai, Akiyoshi Hashimoto, Masayuki Koyama, Nobutaka Nagano in Heart and Vessels (2019)

  11. No Access

    Article

    Late aneurysm formation of Valsalva sinus after aortic valve replacement due to Takayasu’s arteritis

    Takayasu’s arteritis (TA) is an inflammatory disease of unknown etiology involving the aorta and its branches, and also causes aortic regurgitation (AR). One of the most serious but rare complications after ao...

    Akira Funada, Hideaki Kanzaki, Nobutaka Nagano, Yasuo Sugano in Heart and Vessels (2015)