10 Result(s)
within
English
Science, Humanities and Social Sciences, multidisciplinary
Science, Humanities and Social Sciences, multidisciplinary
Nitin S. Baliga
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Article
Open AccessComparison of the transcriptome, lipidome, and c-di-GMP production between BCGΔBCG1419c and BCG, with Mincle- and Myd88-dependent induction of proinflammatory cytokines in murine macrophages
We have previously reported the transcriptomic and lipidomic profile of the first-generation, hygromycin-resistant (HygR) version of the BCGΔBCG1419c vaccine candidate, under biofilm conditions. We recently const...
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Article
Open AccessConsequential insights for advancing informal STEM learning and outcomes for students from historically marginalized communities
Consequential STEM experiences in informal settings can address issues of equity by fully engaging historically marginalized high school students in complex socio-scientific issues. However, inclusive and effe...
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Article
Open AccessA comprehensive spectral assay library to quantify the Halobacterium salinarum NRC-1 proteome by DIA/SWATH-MS
Data-Independent Acquisition (DIA) is a mass spectrometry-based method to reliably identify and reproducibly quantify large fractions of a target proteome. The peptide-centric data analysis strategy employed i...
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Open AccessGrowth phase estimation for abundant bacterial populations sampled longitudinally from human stool metagenomes
Longitudinal sampling of the stool has yielded important insights into the ecological dynamics of the human gut microbiome. However, human stool samples are available approximately once per day, while commensa...
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Article
Open AccessA comprehensive spectral assay library to quantify the Escherichia coli proteome by DIA/SWATH-MS
Data-Independent Acquisition (DIA) is a method to improve consistent identification and precise quantitation of peptides and proteins by mass spectrometry (MS). The targeted data analysis strategy in DIA relie...
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Article
Open AccessOcean acidification conditions increase resilience of marine diatoms
The fate of diatoms in future acidified oceans could have dramatic implications on marine ecosystems, because they account for ~40% of marine primary production. Here, we quantify resilience of Thalassiosira pseu...
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Article
Open AccessA comprehensive map of genome-wide gene regulation in Mycobacterium tuberculosis
Mycobacterium tuberculosis (MTB) is a pathogenic bacterium responsible for 12 million active cases of tuberculosis (TB) worldwide. The complexity and critical regulatory components of MTB pathogenicity are still ...
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Article
Open AccessThe DNA-binding network of Mycobacterium tuberculosi s
Mycobacterium tuberculosis (MTB) infects 30% of all humans and kills someone every 20–30 s. Here we report genome-wide binding for ~80% of all predicted MTB transcription factors (TFs), and assayed global express...
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Open AccessCommunity-integrated omics links dominance of a microbial generalist to fine-tuned resource usage
Microbial communities are complex and dynamic systems that are primarily structured according to their members’ ecological niches. To investigate how niche breadth (generalist versus specialist lifestyle strat...
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Article
Correction: Corrigendum: Peroxiredoxins are conserved markers of circadian rhythms
Nature 485, 459–464 (2012); doi:10.1038/nature11088 In the author list of this Article, the names of Gerben van Ooijen and Maria Olmedo should also have been asterisked, indicating their equal contributions. T...
