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Article
Open AccessMulti-omics analysis of human tendon adhesion reveals that ACKR1-regulated macrophage migration is involved in regeneration
Tendon adhesion is a common complication after tendon injury with the development of accumulated fibrotic tissues without effective anti-fibrotic therapies, resulting in severe disability. Macrophages are wide...
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Article
Open AccessGlobal fungal-host interactome map** identifies host targets of candidalysin
Candidalysin, a cytolytic peptide toxin secreted by the human fungal pathogen Candida albicans, is critical for fungal pathogenesis. Yet, its intracellular targets have not been extensively mapped. Here, we perfo...
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Article
Oral Microbiota: A New Insight into Cancer Progression, Diagnosis and Treatment
The polymorphic microbiome has been defined as one of the “Hallmarks of Cancer”. Extensive studies have now uncovered the role of oral microbiota in cancer development and progression. Bacteria, fungi, archaea...
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Article
Open AccessMulti-kingdom microbiota analyses identify bacterial–fungal interactions and biomarkers of colorectal cancer across cohorts
Despite recent progress in our understanding of the association between the gut microbiome and colorectal cancer (CRC), multi-kingdom gut microbiome dysbiosis in CRC across cohorts is unexplored. We investigat...
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Open AccessANLN promotes carcinogenesis in oral cancer by regulating the PI3K/mTOR signaling pathway
Oral cancer is a malignant disease that threatenshuman life and greatly reducespatientquality of life. ANLN was reported to promote the progression of cancer. This study aims to investigate the role of ANLNin ...
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Open AccessIdentification of microbial markers across populations in early detection of colorectal cancer
Associations between gut microbiota and colorectal cancer (CRC) have been widely investigated. However, the replicable markers for early-stage adenoma diagnosis across multiple populations remain elusive. Here...
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Open AccessMicrobiome dysbiosis in lung cancer: from composition to therapy
The correlations between microbiota dysbiosis and cancer have gained extensive attention and been widely explored. As a leading cancer diagnosis worldwide, lung cancer poses a great threat to human health. The...
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Article
Open AccessRanibizumab Pretreatment in Vitrectomy with Internal Limiting Membrane Peeling on Diabetic Macular Edema in Severe Proliferative Diabetic Retinopathy
To evaluate the efficacy of intravitreal ranibizumab (IVR) pretreatment for pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling in severe proliferative diabetic retinopathy (PDR) combined...
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Article
Phase- and epidemic region-adjusted estimation of the number of coronavirus disease 2019 cases in China
The outbreak of the coronavirus disease 2019 was first reported in Wuhan in December 2019 and gradually spread to other areas in China. After implementation of prevention and control measures, the estimation o...
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Article
An asymmetric supercapacitor based on NiCo2O4 nanosheets as anode and partially reduced graphene oxides/carbon nanotubes as cathode
Nickel–cobalt oxide has been given more attention to being used as the supercapacitor's electrode materials due to its two-dimensional layered structure, good electron conductivity, and excellent stability. In...
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Article
Supercapacitors based on free-standing reduced graphene oxides/carbon nanotubes hybrid films
The freestanding of reduced graphene oxides/carbon nanotubes (rGO/CNTs) hybrid films are synthesized via the simple vacuum filtration and thermal reduction methods. And the electrochemical behaviors of rGO/CNT...
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Open AccessRetraction Note: Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis
The authors are retracting this article [1] after an investigation by the Ethics Committee of the Fourth Military Medical University (**’an, Shaanxi, China) of the following concerns that had been raised with ...
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Base-resolution stratification of cancer mutations using functional variomics
This massively parallel pipeline enables high-throughput generation and confirmation of variants by Gateway cloning, barcoding, and next-generation sequencing, and their stratification by multiplexed interacti...
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Open AccessRETRACTED ARTICLE: Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis
The onset of distal metastasis, which underlies the high mortality of breast cancers, warrants substantial studies to depict its molecular basis. Nuclear factor of activated T cells 5 (NFAT5) is upregulated in...
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Article
A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length