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  1. Article

    Open Access

    Evaluation of combination treatment with DS-1205c, an AXL kinase inhibitor, and osimertinib in metastatic or unresectable EGFR-mutant non-small cell lung cancer: results from a multicenter, open-label phase 1 study

    The objective of this study was to evaluate the safety and tolerability of DS-1205c, an oral AXL-receptor inhibitor, in combination with osimertinib in metastatic or unresectable EFGR-mutant non-small cell lung c...

    James Chih-Hsin Yang, Wu-Chou Su, Chao-Hua Chiu… in Investigational New Drugs (2023)

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    Article

    Evaluation of pulsed high intensity focused ultrasound exposures on metastasis in a murine model

    High intensity focused ultrasound (HIFU) may be employed in two ways: continuous exposures for thermal ablation of tissue (>60°C), and pulsed-exposures for non-ablative effects, including low temperature hyper...

    Hilary Hancock, Matthew R. Dreher, Nigel Crawford… in Clinical & Experimental Metastasis (2009)

  3. No Access

    Article

    Metastasis Predictive Signature Profiles Pre-exist in Normal Tissues

    Previous studies from our laboratory have demonstrated that metastatic propensity is significantly influenced by the genetic background upon which tumors arise. We have also established that human gene express...

    Haiyan Yang, Nigel Crawford, Luanne Lukes… in Clinical & Experimental Metastasis (2005)