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    Gene expression pathway analysis to predict response to neoadjuvant docetaxel and capecitabine for breast cancer

    Neoadjuvant chemotherapy has been shown to be equivalent to post-operative treatment for breast cancer, and allows for assessment of chemotherapy response. In a pilot trial of docetaxel (T) and capecitabine (X...

    Larissa A. Korde, Lara Lusa, Lisa McShane in Breast Cancer Research and Treatment (2010)

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    The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival

    Microarray expression signature analyses have suggested that extracellular matrix (ECM) gene dysregulation is predictive of metastasis in both mouse mammary tumorigenesis and human breast cancer. We have previ...

    Nigel P. S. Crawford, Renard C. Walker, Luanne Lukes in Clinical & Experimental Metastasis (2008)

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    Metastasis Predictive Signature Profiles Pre-exist in Normal Tissues

    Previous studies from our laboratory have demonstrated that metastatic propensity is significantly influenced by the genetic background upon which tumors arise. We have also established that human gene express...

    Haiyan Yang, Nigel Crawford, Luanne Lukes in Clinical & Experimental Metastasis (2005)

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    Caffeine suppresses metastasis in a transgenic mouse model: a prototype molecule for prophylaxis of metastasis

    A significant fraction of cancer patients have occult disseminated tumors at the time of primary diagnosis, which usually progress to become clinically relevant lesions. Since the majority of cancer mortality ...

    Haiyan Yang, Jessica Rouse, Luanne Lukes in Clinical & Experimental Metastasis (2005)

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    Comparative sequence analysis in eight inbred strains of the metastasis modifier QTL candidate gene Brms1

    Yeong-Gwan Park, Luanne Lukes, Howard Yang, Michael T. Debies in Mammalian Genome (2002)