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Article

Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1

Although NGLY1 is known as a pivotal enzyme that catalyses the deglycosylation of denatured glycoproteins, information regarding the responses of human cancer and normal cells to NGLY1 suppression is limited.

Ashwini Zolekar, Victor. J. T. Lin, Nigam M. Mishra… in British Journal of Cancer (2018)