3 Result(s)
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Nicole Vincent Jordan
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Article
Open AccessPAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer
High-grade serous ovarian cancers (HGSOC) represent the most common subtype of ovarian malignancies. Due to the frequency of late-stage diagnosis and high rates of recurrence following standard of care treatme...
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Article
Open AccessExpression of β-globin by cancer cells promotes cell survival during blood-borne dissemination
Metastasis-competent circulating tumour cells (CTCs) experience oxidative stress in the bloodstream, but their survival mechanisms are not well defined. Here, comparing single-cell RNA-Seq profiles of CTCs fro...
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Article
HER2 expression identifies dynamic functional states within circulating breast cancer cells
Patient-derived circulating tumour cells are used to characterize the dynamics and underlying plasticity of HER2 expression in non-HER2-amplified breast tumours.
