13 Result(s)

Article

Risk factors for grade 3/4 transaminase elevation in patients with chronic lymphocytic leukemia treated with idelalisib

Jennifer R. Brown, Andrew Zelenetz, Richard Furman, Nicole Lamanna… in Leukemia (2020)

Article

Is There a Role for Chemotherapy in the Era of Targeted Therapies?

The treatment landscape of chronic lymphocytic leukemia has been rapidly evolving over the past few years. The prior standard of care, chemoimmunotherapy, is being replaced by targeted agents, and the utility ...

Jason C. Lee, Nicole Lamanna in Current Hematologic Malignancy Reports (2020)

Article

Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia

Genomic analyses of chronic lymphocytic leukemia (CLL) identified somatic mutations and associations of clonal diversity with adverse outcomes. Clonal evolution likely has therapeutic implications but its dyna...

Alexander C. Leeksma, Justin Taylor, Bian Wu, Jeffrey R. Gardner, Jie He… in Leukemia (2019)

Article

Evolving Strategies for the Treatment of Chronic Lymphocytic Leukemia in the Upfront Setting

Chronic lymphocytic leukemia (CLL) is a disease of marked clinical heterogeneity, and while some patients have a normal life expectancy, others develop rapidly progressive disease shortly after diagnosis. The ...

Spencer H. Bachow, Nicole Lamanna in Current Hematologic Malignancy Reports (2016)

Article

Association of health-related quality of life with gender in patients with B-cell chronic lymphocytic leukemia

This analysis examined associations between gender and health-related quality of life (HRQOL) in patients with B-cell chronic lymphocytic leukemia (CLL) as they initiate therapy for CLL outside the clinical tr...

Chris L. Pashos, Christopher R. Flowers, Neil E. Kay… in Supportive Care in Cancer (2013)

Article

Treatment of Older Patients with Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) is typically a disease of older individuals. Yet most of the literature on various chemotherapeutic regimens includes patients who are 10 to 15 years younger than the median ...

Nicole Lamanna in Current Hematologic Malignancy Reports (2012)

Article

Challenges in the Frontline Treatment of Patients With Chronic Lymphocytic Leukemia

Therapy for chronic lymphocytic leukemia has improved dramatically over the past 20 years. Traditional therapy with oral chlorambucil led to complete responses in less than 5% of treated patients, in marked co...

Nicole Lamanna in Current Hematologic Malignancy Reports (2010)

Article

Chemoimmunotherapy with modified dosing of fludarabine, cyclophosphamide, and rituximab shows significant clinical activity in patients with previously untreated chronic lymphocytic leukemia

Nicole Lamanna, Mark A. Weiss in Current Hematologic Malignancy Reports (2009)

Article

Incorporating prognostic information into treatment decisions in chronic lymphocytic leukemia

Most patients with chronic lymphocytic leukemia are diagnosed at an early stage, when traditional staging systems fail to distinguish those with an aggressive disease course from those with an excellent progno...

Nitin Jain, Nicole Lamanna in Current Oncology Reports (2009)

Article

Consolidation and maintenance rituximab therapy in chronic lymphocytic leukemia

Nicole Lamanna, Mark A. Weiss in Current Oncology Reports (2008)

Chapter

Relapsed Acute Lymphoblastic Leukemia

Treatment of acute lymphoblastic leukemia in children is one of the great success stories of combination chemotherapy. Unfortunately, adults fare much worse and the majority of adult patients ultimately fail t...

Nicole Lamanna, Melissa von Hassel, Mark Weiss in Acute Leukemias (2008)