-
Article
Open AccessMutational signatures among young-onset testicular cancers
Incidence of testicular cancer is highest among young adults and has been increasing dramatically for men born since 1945. This study aimed to elucidate the factors driving this trend by investigating differen...
-
Article
Examining the etiology of early-onset breast cancer in the Canadian Partnership for Tomorrow’s Health (CanPath)
Breast cancer incidence among younger women (under age 50) has increased over the past 25 years, yet little is known about the etiology among this age group. The objective of this study was to investigate rela...
-
Article
Open AccessMutational landscape differences between young-onset and older-onset breast cancer patients
The incidence of breast cancer among young women (aged ≤40 years) has increased in North America and Europe. Fewer than 10% of cases among young women are attributable to inherited BRCA1 or BRCA2 mutations, sugge...