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Article
Open AccessAnti-diarrheal drug loperamide induces dysbiosis in zebrafish microbiota via bacterial inhibition
Perturbations of animal-associated microbiomes from chemical stress can affect host physiology and health. While dysbiosis induced by antibiotic treatments and disease is well known, chemical, nonantibiotic dr...
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Article
Open AccessLabel-free imaging of red blood cells and oxygenation with color third-order sum-frequency generation microscopy
Map** red blood cells (RBCs) flow and oxygenation is of key importance for analyzing brain and tissue physiology. Current microscopy methods are limited either in sensitivity or in spatio-temporal resolution...
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Article
Open AccessLocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images
Quantitative imaging of epithelial tissues requires bioimage analysis tools that are widely applicable and accurate. In the case of imaging 3D tissues, a common preprocessing step consists of projecting the ac...
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Article
Open AccessDual-color deep-tissue three-photon microscopy with a multiband infrared laser
Multiphoton microscopy combined with genetically encoded fluorescent indicators is a central tool in biology. Three-photon (3P) microscopy with excitation in the short-wavelength infrared (SWIR) water transpar...
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Article
Open AccessA metameric origin for the annelid pygidium?
Segmented body organizations are widely represented in the animal kingdom. Whether the last common bilaterian ancestor was already segmented is intensely debated. Annelids display broad morphological diversity...
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Article
Open AccessFeatures of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genes
The ParaHox gene cluster is the evolutionary sister to the Hox cluster. Whilst the role of the Hox cluster in patterning the anterior-posterior axis of bilaterian animals is well established, and the organisat...
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Article
Open Accessatonal- and achaete-scute-related genes in the annelid Platynereis dumerilii: insights into the evolution of neural basic-Helix-Loop-Helix genes
Functional studies in model organisms, such as vertebrates and Drosophila, have shown that basic Helix-loop-Helix (bHLH) proteins have important roles in different steps of neurogenesis, from the acquisition of n...
