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Article
Ser/Thr kinases and polyamines in the regulation of non-canonical functions of elongation factor 1A
The link between eukaryotic translation elongation factor 1A (eEF1A) and signal transduction pathways through the regulatory mechanism of phosphorylation has never been considered. In this review, we focus on ...
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Article
Open AccessBioengineered Silicon Diatoms: Adding Photonic Features to a Nanostructured Semiconductive Material for Biomolecular Sensing
Native diatoms made of amorphous silica are first converted into silicon structures via magnesiothermic process, preserving the original shape: electron force microscopy analysis performed on silicon-converted...
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Article
Open AccessB-cell receptor-guided delivery of peptide-siRNA complex for B-cell lymphoma therapy
Despite the clinical response of conventional anticancer therapy, including chemotherapeutic treatments, radiation therapy and corticosteroids, tumorigenic B-cell lymphomas show an incomplete response to clini...
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Article
Open AccessDiatomite silica nanoparticles for drug delivery
Diatomite is a natural fossil material of sedimentary origin, constituted by fragments of diatom siliceous skeletons. In this preliminary work, the properties of diatomite nanoparticles as potential system for...
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Article
The magic spot ppGpp influences in vitro the molecular and functional properties of the elongation factor 1α from the archaeon Sulfolobus solfataricus
Guanosine tetra-phosphate (ppGpp), also known as “magic spot I”, is a key molecule in the stringent control of most eubacteria and some eukarya. Here, we show that ppGpp affects the functional and molecular pr...
