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Article
Open AccessKaryopherins: potential biological elements involved in the delayed graft function in renal transplant recipients
Immediately after renal transplantation, patients experience rapid and significant improvement of their clinical conditions and undergo considerable systemic and cellular modifications. However, some patients ...
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Article
Open AccessMolecular pathways undergoing dramatic transcriptomic changes during tumor development in the human colon
The malignant transformation of precancerous colorectal lesions involves progressive alterations at both the molecular and morphologic levels, the latter consisting of increases in size and in the degree of ce...
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Article
Open AccessRS-SNP: a random-set method for genome-wide association studies
The typical objective of Genome-wide association (GWA) studies is to identify single-nucleotide polymorphisms (SNPs) and corresponding genes with the strongest evidence of association (the 'most-significant SN...
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Article
Open AccessComparative study of gene set enrichment methods
The analysis of high-throughput gene expression data with respect to sets of genes rather than individual genes has many advantages. A variety of methods have been developed for assessing the enrichment of set...
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Article
Open AccessStatistical assessment of discriminative features for protein-coding and non coding cross-species conserved sequence elements
The identification of protein coding elements in sets of mammalian conserved elements is one of the major challenges in the current molecular biology research. Many features have been proposed for automaticall...
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Article
Open AccessPromoter methylation correlates with reduced NDRG2expression in advanced colon tumour
Aberrant DNA methylation of CpG islands of cancer-related genes is among the earliest and most frequent alterations in cancerogenesis and might be of value for either diagnosing cancer or evaluating recurrent ...
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Chapter and Conference Paper
Statistical Assessment of MSigDB Gene Sets in Colon Cancer
Gene expression profiling offers a great opportunity for understanding the key role of genes in alterations which drive a normal cell to a cancer state. A deep understanding of the mechanisms of tumorigenesis ...
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Chapter and Conference Paper
SVD Based Feature Selection and Sample Classification of Proteomic Data
Feature selection becomes a central task when ’signature’ profiles specific to a pathological status have to be extracted from high dimensional gene expression or proteomic data. In the present paper, we propo...
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Chapter and Conference Paper
Prediction of Crohn’s Disease by Profiles of Single Nucleotide Polymorphisms
This paper focuses on the comparison of two different approaches to the analysis of Single Nucleotide Polymorphism (SNP) profiles data regarding Crohn’s Disease; the first one is based on a single SNP analysis...
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Article
Open AccessRegularized Least Squares Cancer Classifiers from DNA microarray data
The advent of the technology of DNA microarrays constitutes an epochal change in the classification and discovery of different types of cancer because the information provided by DNA microarrays allows an appr...
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Chapter and Conference Paper
Visual Detection of Hexagonal Headed Bolts Using Method of Frames and Matching Pursuit
In this paper we focus on the problem of automatically detecting the absence of the fastening bolts that secure the rails to the sleepers. The proposed visual inspection system uses images acquired from a digi...
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Article
Optical flow from 1-D correlation: Application to a simple time-to-crash detector
In the first part of this article we show that a new technique exploiting 1-D correlation of 2-D or even 1-D patches between successive frames may be sufficient to compute a satisfactory estimation of the opti...
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Chapter
A time-to-crash detector based on area expansions: Example of an opto-motor reflex
In this paper we show that the rate of change of the area that a moving object projects on the image plane and the temporal behaviour of the time-to-crash between the object and the camera are deeply connected. I...
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Chapter and Conference Paper
A fast obstacle detection method based on optical flow
This paper presents a methodology, based on the estimation of the optical flow, to detect static obstacles during the motion of a mobile robot. The algorithm is based on a correlation scheme. At any time, we e...
