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Article
Incidence, clinical features and diagnosis of cicatrising conjunctivitis in Australia and New Zealand
This study aimed to determine the incidence, clinical features and management of cicatrising conjunctivitis in Australia and New Zealand, also enabling comparison with data from the United Kingdom.
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Article
Open AccessSelf-organized centripetal movement of corneal epithelium in the absence of external cues
Maintaining the structure of the cornea is essential for high-quality vision. In adult mammals, corneal epithelial cells emanate from stem cells in the limbus, driven by an unknown mechanism towards the centre...
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Article
Open AccessClinical outcomes of xeno-free expansion and transplantation of autologous ocular surface epithelial stem cells via contact lens delivery: a prospective case series
Depletion of limbal stem cells leads to a debilitating condition known as limbal stem cell deficiency, characterised by impaired corneal wound healing and poor vision. The aim of this study was to determine wh...
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Article
Open AccessRole of toll-like receptors in human iris pigment epithelial cells and their response to pathogen-associated molecular patterns
Toll-like receptor (TLR) activation is hypothesized to contribute to inflammatory eye disease including uveitis, yet the distribution pattern of TLRs in human uveal tissues remains poorly described. The purpos...
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Chapter
Adult Human Corneal Epithelial Stem Cells
The cornea’s accessibility and visualization with minimally invasive techniques renders it an ideal organ to study SC and their differentiated progeny. The limbus houses, nurtures, and protects a rare populati...
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Article
Tissue-Regenerating, Vision-Restoring Corneal Epithelial Stem Cells
The cornea, the most anterior segment of the eye, provides us with exquisite vision. Unlike other vital tissues, it is poorly protected from the environment and is thus reliant on a self-renewal program to pre...
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Article
The effect of ultraviolet radiation on choroidal melanocytes and melanoma cell lines: cell survival and matrix metalloproteinase production
Ultraviolet radiation (UVR) can induce DNA damage and regulate the expression of factors important for tumour growth and metastasis, including matrix metalloproteinases (MMPs). Epidemiological studies suggest ...
