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  1. Article

    Open Access

    SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer

    Patients with triple-negative breast cancers (TNBC) are at a high risk for a recurrent or metastatic disease, and the molecular mechanisms associated with this risk are unclear. Proteoglycan serglycin (SRGN) p...

    Z Zhang, Y Deng, G Zheng, X Jia, Y **ong, K Luo, Q Qiu, Ni Qiu, J Yin, M Lu… in Oncogenesis (2017)

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  2. No Access

    Article

    LINC01638 lncRNA activates MTDH-Twist1 signaling by preventing SPOP-mediated c-Myc degradation in triple-negative breast cancer

    Breast cancer is a heterogeneous disease, and triple-negative breast cancer (TNBC) continues to be a serious health problem. The potential involvement of lncRNAs in TNBC progression remains unexplored. Here, w...

    Liyun Luo, Hailin Tang, Li Ling, Nan Li, **aoting Jia, Zhijie Zhang… in Oncogene (2018)

  3. Article

    Open Access

    FOXO3a-driven miRNA signatures suppresses VEGF-A/NRP1 signaling and breast cancer metastasis

    Metastasis remains the major obstacle to improved survival for breast cancer patients. Downregulation of FOXO3a transcription factor in breast cancer is causally associated with the development of metastasis t...

    Ying Song, Shanshan Zeng, Guopei Zheng, Danyang Chen, Pan Li, Mingqiang Yang… in Oncogene (2021)

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