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Article
Open AccessPresence of intratumoral platelets is associated with tumor vessel structure and metastasis
Platelets play a fundamental role in maintaining hemostasis and have been shown to participate in hematogenous dissemination of tumor cells. Abundant platelets were detected in the tumor microenvironment outsi...
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Article
Open AccessExogenous IFN-beta regulates the RANKL-c-Fos-IFN-beta signaling pathway in the collagen antibody-induced arthritis model
Although a variety of drugs have been used to treat the symptoms of rheumatoid arthritis (RA), none of them are able to cure the disease. Interferon β (IFN-β) has pleiotropic effects on RA, but whether it can ...
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Article
Open AccessInternational trends in primary liver cancer incidence from 1973 to 2007
Primary liver cancer (PLC) is a common cancer worldwide, especially in develo** countries. Several previous studies using different datasets have summarized PLC incidence rates and trends in different popula...
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Article
Open AccessAngiopoietin-2 impairs collateral artery growth associated with the suppression of the infiltration of macrophages in mouse hindlimb ischaemia
Angiopoietin-2 (Ang-2), a ligand of the Tie-2 receptor, plays an important role in maintaining endothelial cells and in destabilizing blood vessels. Collateral artery growth (arteriogenesis) is a key adaptive ...
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Article
Open AccessTianzhi granule improves cognition and BPSD of vascular dementia: a randomized controlled trial
Tianzhi granule (TZ) is usually used for patients with vascular dementia (VaD) in China. The aim was to assess the effect of TZ by a randomized clinical trial (RCT).