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Open AccessAuthor Correction: Glycopeptide database search and de novo sequencing with PEAKS GlycanFinder enable highly sensitive glycoproteomics
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Open AccessGlycopeptide database search and de novo sequencing with PEAKS GlycanFinder enable highly sensitive glycoproteomics
Here we present GlycanFinder, a database search and de novo sequencing tool for the analysis of intact glycopeptides from mass spectrometry data. GlycanFinder integrates peptide-based and glycan-based search s...
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Article
Open AccessDeep neural network for detecting arbitrary precision peptide features through attention based segmentation
A promising technique of discovering disease biomarkers is to measure the relative protein abundance in multiple biofluid samples through liquid chromatography with tandem mass spectrometry (LC-MS/MS) based qu...
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Open AccessGenetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data
The under-representation of several ethnic groups in existing genetic databases and studies have undermined our understanding of the genetic variations and associated traits or diseases in many populations. Co...
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Open AccessDeepIso: A Deep Learning Model for Peptide Feature Detection from LC-MS map
Liquid chromatography with tandem mass spectrometry (LC-MS/MS) based quantitative proteomics provides the relative different protein abundance in healthy and disease-afflicted patients, which offers the inform...
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Open AccessComplete De Novo Assembly of Monoclonal Antibody Sequences
De novo protein sequencing is one of the key problems in mass spectrometry-based proteomics, especially for novel proteins such as monoclonal antibodies for which genome information is often limited or not availa...
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Open AccessCounting motifs in the human interactome
Small over-represented motifs in biological networks often form essential functional units of biological processes. A natural question is to gauge whether a motif occurs abundantly or rarely in a biological ne...