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Article
Open AccessCombined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer
Germline CDH1 pathogenic or likely pathogenic variants cause hereditary diffuse gastric cancer (HDGC). Once a genetic cause is identified, stomachs’ and breasts’ surveillance and/or prophylactic surgery is offere...
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Chapter and Conference Paper
Energy Savings in Residential Buildings Based on Adaptive Thermal Comfort Models
The residential Heating, Ventilation and Air Conditioning (HVAC) systems nowadays aim to provide tailored solutions, focused on the home occupants’ thermal comfort. In that sense, these systems must support th...
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Chapter
Developments in the Computation of Reduced Order Models with the Use of Dominant Spectral Zeros
In this report we present a study on the computation of dominant spectral-zeros (DSZ) of a full order model (FOM) and its application to determining a passivity-preserving reduced order model (ROM). The study ...
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Chapter and Conference Paper
Tracking Anterior Mitral Leaflet in Echocardiographic Videos Using Morphological Operators and Active Contours
Rheumatic heart disease is the result of damage to the heart valves, more often the mitral valve. The heart valves leaflets get inflamed, scarred and stretched which interrupts the normal blood flow, resulting...
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Article
Open AccessEvidence-based malaria control in Timor Leste from 2006 to 2012
Malaria has been a major public health problem in the newly established Democratic Republic of Timor Leste with over 200,000 cases being reported in 2006 and 2007. The National Malaria Control Programme (NMCP)...
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Chapter
Model Order Reduction: Methods, Concepts and Properties
This chapter offers an introduction to Model Order Reduction (MOR). It gives an overview on the methods that are mostly used. It also describes the main concepts behind the methods and the properties that are ...
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Article
Open AccessImplementing what works: a case study of integrated primary health care revitalisation in Timor-Leste
Revitalising primary health care (PHC) and the need to reach MDG targets requires develo** countries to adapt current evidence about effective health systems to their local context. Timor-Leste in one of the...
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Article
Open AccessStriving for better health through health research in post-conflict Timor-Leste
The Cabinet of Health Research and Development (CHRD) has recently been established as the first health research institute in one of the world's newest nations, Timor-Leste. We discuss the development of this ...
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Article
Open AccessMalaria control in Timor-Leste during a period of political instability: what lessons can be learned?
Malaria is a major global health problem, often exacerbated by political instability, conflict, and forced migration.
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Article
Der SETAC Europe Student Advisory Council (SAC)