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  1. Article

    Open Access

    Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer

    Germline CDH1 pathogenic or likely pathogenic variants cause hereditary diffuse gastric cancer (HDGC). Once a genetic cause is identified, stomachs’ and breasts’ surveillance and/or prophylactic surgery is offere...

    Celina São José, José Garcia-Pelaez, Marta Ferreira, Oscar Arrieta in Gastric Cancer (2023)

  2. No Access

    Chapter and Conference Paper

    Energy Savings in Residential Buildings Based on Adaptive Thermal Comfort Models

    The residential Heating, Ventilation and Air Conditioning (HVAC) systems nowadays aim to provide tailored solutions, focused on the home occupants’ thermal comfort. In that sense, these systems must support th...

    Rodrigo Almeida, Petia Georgieva, Nelson Martins in Pattern Recognition and Image Analysis (2022)

  3. No Access

    Chapter

    Developments in the Computation of Reduced Order Models with the Use of Dominant Spectral Zeros

    In this report we present a study on the computation of dominant spectral-zeros (DSZ) of a full order model (FOM) and its application to determining a passivity-preserving reduced order model (ROM). The study ...

    Francisco Damasceno Freitas, Joost Rommes in Realization and Model Reduction of Dynamic… (2022)

  4. No Access

    Chapter and Conference Paper

    Tracking Anterior Mitral Leaflet in Echocardiographic Videos Using Morphological Operators and Active Contours

    Rheumatic heart disease is the result of damage to the heart valves, more often the mitral valve. The heart valves leaflets get inflamed, scarred and stretched which interrupts the normal blood flow, resulting...

    Malik Saad Sultan, Nelson Martins, Eva Costa in Biomedical Engineering Systems and Technol… (2018)

  5. Article

    Open Access

    Evidence-based malaria control in Timor Leste from 2006 to 2012

    Malaria has been a major public health problem in the newly established Democratic Republic of Timor Leste with over 200,000 cases being reported in 2006 and 2007. The National Malaria Control Programme (NMCP)...

    Manel AMG Yapabandara, Raul Sarmento, Maria do Rosario de Fatima Mota in Malaria Journal (2015)

  6. No Access

    Chapter

    Model Order Reduction: Methods, Concepts and Properties

    This chapter offers an introduction to Model Order Reduction (MOR). It gives an overview on the methods that are mostly used. It also describes the main concepts behind the methods and the properties that are ...

    Athanasios C. Antoulas, Roxana Ionutiu in Coupled Multiscale Simulation and Optimiza… (2015)

  7. Article

    Open Access

    Implementing what works: a case study of integrated primary health care revitalisation in Timor-Leste

    Revitalising primary health care (PHC) and the need to reach MDG targets requires develo** countries to adapt current evidence about effective health systems to their local context. Timor-Leste in one of the...

    Nelson Martins, Lyndal J Trevena in Asia Pacific Family Medicine (2014)

  8. Article

    Open Access

    Striving for better health through health research in post-conflict Timor-Leste

    The Cabinet of Health Research and Development (CHRD) has recently been established as the first health research institute in one of the world's newest nations, Timor-Leste. We discuss the development of this ...

    Nelson Martins, Zoe Hawkins in Health Research Policy and Systems (2012)

  9. Article

    Open Access

    Malaria control in Timor-Leste during a period of political instability: what lessons can be learned?

    Malaria is a major global health problem, often exacerbated by political instability, conflict, and forced migration.

    Joao S Martins, Anthony B Zwi, Nelson Martins, Paul M Kelly in Conflict and Health (2009)

  10. No Access

    Article

    Der SETAC Europe Student Advisory Council (SAC)

    Thomas -Benjamin Seiler, Amy Brooks in Umweltwissenschaften und Schadstoff-Forsch… (2007)